Improving neuronal cell function with cell permeable copper complexes

Grant number: DP110101368 | Funding period: 2011 - 2013

Completed

Abstract

Metal-based drugs offer an exciting new approach to treatment of neurodegeneration. However, little is known about how cells metabolise these drugs and this information is critical for further drug development. This project will determine how metal-based drugs are metabolised by neuronal cells and how this may result in therapeutic benefit.

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Deregulation of biometal homeostasis: the missing link for neuronal ceroid lipofuscinoses?

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University of Melbourne Researchers