How bacteria evolve and cause disease
Grant number: 1008549 | Funding period: 2011 - 2015
Bacteria have evolved different ways of causing disease in humans. Some bacteria produce toxins that attack the host or they have developed ways to persist in the host by evading immune responses and resisting antibiotics. This project is concerned with understanding how these processes occur and developing preventative strategies for two important groups of bacteria that cause disease in humans, including the bacteria that cause TB and the devastating skin disease Buruli ulcer, and the hospital superbug "Golden Staph".
Related publications (1)
Adaptive Change Inferred from Genomic Population Analysis of the ST93 Epidemic Clone of Community-Associated Methicillin-Resistant Staphylococcus aureus
Timothy P Stinear, Kathryn E Holt, Kyra Chua, Justin Stepnell, Kellie L Tuck, Geoffrey Coombs, Paul Francis Harrison, Torsten Seemann, Benjamin P Howden