TREATING CANCER BY TARGETING GENE MUTATIONS

Clustered somatic mutations are frequent in transcription factor binding motifs within proximal promoter regions in melanoma and other cutaneous malignancies

Andrew J Colebatch, Leon Di Stefano, Stephen Q Wong, Ross D Hannan, Paul M Waring, Alexander Dobrovic, Grant A McArthur, Anthony T Papenfuss

2016-10-11

Desmoglein 2 promotes vasculogenic mimicry in melanoma and is associated with poor clinical outcome

Lih Yin Tan, Chris Mintoff, M Zahied Johan, Brenton W Ebert, Clare Fedele, You Fang Zhang, Pacman Szeto, Karen E Sheppard, Grant A McArthur, Erwin Foster-Smith, Andrew Ruszkiewicz, Michael P Brown, Claudine S Bonder, Mark Shackleton, Lisa M Ebert

2016-07-19

Whole exome sequencing identifies a recurrent RQCD1 P131L mutation in cutaneous melanoma

SQ Wong, A Behren, VJ Mar, K Woods, J Li, C Martin, KE Sheppard, R Wolfe, J Kelly, J Cebon, A Dobrovic, GA McArthur

2015-01-01

Melanoma is often caused by mutations due to exposure to ultraviolet radiation. This study reports a recurrent somatic C > T chang..