To Repair an Osteo-Chondral Defect in an Experimental Rabbit Model Using a Structured 3d Nano-Composite Scaffold Loaded With Mesenchymal Stem Cells (Msc)

Grant number: 1017633 | Funding period: 2011 - 2014

Completed

Abstract

The treatment of cartilage damage is a major problem in orthopaedic practice. The use of a 3D scaffold may overcome many challenges associated with cartilage and bone repair and regeneration. The aim of this research is to culture bone and cartilage cells into a prefabricated scaffold which may then be tested in an animal model. The results of this research may offer a new method of treating post-traumatic and osteoarthritic defects.

Related publications (3)

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The aim of this pilot project was to introduce a novel use of acellular dermal matrix (ADM) in combination with infrapatellar fat ..

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Acellular dermal matrix (ADM) has been in clinical use for decades in numerous surgical applications. The ability for ADM to promo..

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Infrapatellar fat pad adipose stem cells (IPFP-ASCs) have been shown to harbor chondrogenic potential. When combined with 3D polym..

University of Melbourne Researchers

Peter Choong