CAREER DEVELOPMENT AWARD - CLINICAL

Grant number: 490970 | Funding period: 2011 - 2011

Completed

Abstract

Recent evidence has pointed to the beginning of pregnancy as the time when biological cascades begin that cause common diseases of pregnancy. This opens the door to developing bloods test in early pregnancy predicting who will develop problems, and to hunt for novel proteins in the bloodstream that are causing the illnesses. 'Proteomic technology' will be used, a new cutting edge tool that can scan the entire protein pool in mum's blood in a single experiment.

Related publications (9)

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Circulating RNA coding genes regulating apoptosis in maternal blood in severe early onset fetal growth restriction and pre-eclampsia

CL Whitehead, SP Walker, M Lappas, S Tong

2013-08-01

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The use of miRNA microarrays for the analysis of cancer samples with global miRNA decrease

Di Wu, Yifang Hu, Stephen Tong, Bryan RG Williams, Gordon K Smyth, Michael P Gantier

2013-07-01

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Corin, an enzyme with a putative role in spiral artery remodeling, is up-regulated in late secretory endometrium and first trimester decidua

Tu'uhevaha J Kaitu'u-Lino, Louie Ye, Laura Tuohey, Evdokia Dimitriadis, Judith Bulmer, Peter Rogers, Ellen Menkhorst, Michelle Van Sinderen, Jane E Girling, Natalie Hannan, Stephen Tong

2013-05-01

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MT-MMPs in pre-eclamptic placenta: Relationship to soluble endoglin production

TJ Kaitu'u-Lino, L Tuohey, L Ye, K Palmer, M Skubisz, S Tong

2013-02-01

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Targeted Nanoparticle Delivery of Doxorubicin Into Placental Tissues to Treat Ectopic Pregnancies

Tu'uhevaha J Kaitu'u-Lino, Scott Pattison, Louie Ye, Laura Tuohey, Pavel Sluka, Jennifer MacDiarmid, Himanshu Brahmbhatt, Terrence Johns, Andrew W Horne, Jeremy Brown, Stephen Tong

2013-02-01

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Using a decline in serum hCG between days 0-4 to predict ectopic pregnancy treatment success after single-dose methotrexate: a retrospective cohort study

Monika Skubisz, Philip Dutton, William Colin Duncan, Andrew W Horne, Stephen Tong

2013-02-01

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MMP-15 Is Upregulated in Preeclampsia, but Does Not Cleave Endoglin to Produce Soluble Endoglin

Tu'uhevaha J Kaitu'u-Lino, Kirsten Palmer, Laura Tuohey, Louie Ye, Stephen Tong

2012-06-29

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Diagnostic Accuracy of Maternal Serum Macrophage Inhibitory Cytokine-1 and Pregnancy-Associated Plasma Protein-A at 6-10 Weeks of Gestation to Predict Miscarriage

Stephen Tong, Gene-Lyn Ngian, Joseph L Onwude, Michael Permezel, Burcu Saglam, Sarah Hay, Justin C Konje, Tim H Marczylo, Gabrielle Fleming, Susan P Walker, Martha Lappas

2012-05-01

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Serum Concentrations of Soluble Flt-1 Are Decreased among Women with a Viable Fetus and No Symptoms of Miscarriage Destined for Pregnancy Loss

Tu'uhevaha J Kaitu'u-Lino, Clare L Whitehead, Gene-Lyn Ngian, Michael Permezel, Stephen Tong

2012-02-28

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