Novel And Objective Methods For Monitoring Neurodegenerative Disease
Grant number: 1012302 | Funding period: 2011 - 2015
It is difficult to monitor disease progression in some neurodegenerative disorders like Huntington’s disease or types of dementia without using expensive and invasive assessment techniques. Yet, by repeatedly recording and analysing the speech (how we speak, not what we say) of a patient, we build up a picture of how the brain is functioning and changing over time. This will lead to a more personalized approach with more effective treatments being given to the right patients at the right time.
Related publications (25)
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Deep brain stimulation wash-in and wash-out times for tremor and speech
Thushara Perera, Shivanthan AC Yohanandan, Adam P Vogel, Colette M McKay, Mary Jones, Richard Peppard, Hugh J McDermott
Parkinson’s disease (PD) and Essential Tremor (ET) are progressive conditions with high world-wide prevalence. Deep Brain Stimulat..
The Feasibility of Using Acoustic Markers of Speech for Optimizing Patient Outcomes during Randomized Amplitude Variation in Deep Brain Stimulation: A Proof of Principle Methods Study.
Adam P Vogel, Hugh J McDermott, Thushara Perera, Mary Jones, Richard Peppard, Colette M McKay
BACKGROUND: Deep brain stimulation (DBS) is an effective treatment for reducing symptoms of tremor. A common and typically subject..
The influence of rate of stimulation and pulse duration on efficacy of deep brain stimulation for Essential Tremor
CM McKay, HJ McDermott, T Perera, R Peppard, M Jones, AP Vogel
Deep brain stimulation (DBS) is used to alleviate tremor in patients diagnosed with Essential Tremor who do not respond to convent..