THE DEVELOPMENT OF THERAPEUTICS FOR PRE-ECLAMPSIA
Grant number: 607219 | Funding period: 2011 - 2013
Related publications (5)
Placental-Specific sFLT-1 e15a Protein Is Increased in Preeclampsia, Antagonizes Vascular Endothelial Growth Factor Signaling, and Has Antiangiogenic Activity
Kirsten R Palmer, Tu'uhevaha J Kaitu'u-Lino, Roxanne Hastie, Natalie J Hannan, Louie Ye, Natalie Binder, Ping Cannon, Laura Tuohey, Terrance G Johns, Alexis Shub, Stephen Tong
In preeclampsia, the antiangiogenic factor soluble fms-like tyrosine kinase-1 (sFLT-1) is released from placenta into the maternal..
MMP-14 Is Expressed in Preeclamptic Placentas and Mediates Release of Soluble Endoglin
Tu'uhevaha J Kaitu'u-Lino, Kirsten R Palmer, Clare L Whitehead, Elizabeth Williams, Martha Lappas, Stephen Tong
Soluble endoglin is an anti-angiogenic protein that is released from the placenta and contributes to both maternal endothelial dys..
Ultrasound Reference Chart Based on IVF Dates to Estimate Gestational Age at 6-9 weeks' Gestation.
Pavitra Delpachitra, Kirsten Palmer, Joseph Onwude, Simon Meagher, Luk Rombauts, Karen Waalwyk, Michael Bethune, Stephen Tong
Accurate determination of gestational age underpins good obstetric care. We assessed the performance of six existing ultrasound re..
Severe Early-Onset Preeclampsia Is Not Associated with a Change in Placental Catechol O-Methyltransferase (COMT) Expression
Kirsten Palmer, Burcu Saglam, Clare Whitehead, Owen Stock, Martha Lappas, Stephen Tong
The genetic deletion of catechol O-methyltransferase (COMT) in mice produces a preeclampsia-like phenotype, with mice exhibiting h..