THE DEVELOPMENT OF THERAPEUTICS FOR PRE-ECLAMPSIA

Assessing the Circulating Placental-Specific Anti-angiogenic Protein sFLT-1 e15a in Preeclampsia.

Kirsten Palmer

2018-01-01

Preeclampsia is a common obstetric complication globally responsible for a significant burden of maternal and perinatal morbidity ..

Placental-Specific sFLT-1 e15a Protein Is Increased in Preeclampsia, Antagonizes Vascular Endothelial Growth Factor Signaling, and Has Antiangiogenic Activity

Kirsten R Palmer, Tu'uhevaha J Kaitu'u-Lino, Roxanne Hastie, Natalie J Hannan, Louie Ye, Natalie Binder, Ping Cannon, Laura Tuohey, Terrance G Johns, Alexis Shub, Stephen Tong

2015-12-01

In preeclampsia, the antiangiogenic factor soluble fms-like tyrosine kinase-1 (sFLT-1) is released from placenta into the maternal..

MMP-14 Is Expressed in Preeclamptic Placentas and Mediates Release of Soluble Endoglin

Tu'uhevaha J Kaitu'u-Lino, Kirsten R Palmer, Clare L Whitehead, Elizabeth Williams, Martha Lappas, Stephen Tong

2012-03-01

Soluble endoglin is an anti-angiogenic protein that is released from the placenta and contributes to both maternal endothelial dys..

Ultrasound Reference Chart Based on IVF Dates to Estimate Gestational Age at 6-9 weeks' Gestation.

Pavitra Delpachitra, Kirsten Palmer, Joseph Onwude, Simon Meagher, Luk Rombauts, Karen Waalwyk, Michael Bethune, Stephen Tong

2012-01-01

Accurate determination of gestational age underpins good obstetric care. We assessed the performance of six existing ultrasound re..

Severe Early-Onset Preeclampsia Is Not Associated with a Change in Placental Catechol O-Methyltransferase (COMT) Expression

Kirsten Palmer, Burcu Saglam, Clare Whitehead, Owen Stock, Martha Lappas, Stephen Tong

2011-06-01

The genetic deletion of catechol O-methyltransferase (COMT) in mice produces a preeclampsia-like phenotype, with mice exhibiting h..