Translational Therapeutics And Diagnostics For Alzheimer'S Disease

Neurological Dysfunction in Early Maturity of a Model for Niemann-Pick C1 Carrier Status

Ya Hui Hung, Mark Walterfang, Leonid Churilov, Lisa Bray, Laura H Jacobson, Kevin J Barnham, Nigel C Jones, Terence J O'Brien, Dennis Velakoulis, Ashley I Bush

2016-07-01

Increased cortical expression of the zinc transporter SLC39A12 suggests a breakdown in zinc cellular homeostasis as part of the pathophysiology of schizophrenia

Elizabeth Scarr, Madhara Udawela, Mark A Greenough, Jaclyn Neo, Myoung Suk Seo, Tammie T Money, Aradhana Upadhyay, Ashley I Bush, Ian P Everall, Elizabeth A Thomas, Brian Dean

2016-03-09

phi XANES: In vivo imaging of metal-protein coordination environments

Simon A James, Dominic J Hare, Nicole L Jenkins, Martin D de Jonge, Ashley I Bush, Gawain McColl

2016-02-10

Amyloid-Beta Peptide Aβ3pE-42 Induces Lipid Peroxidation, Membrane Permeabilization and Calcium-Influx in Neurons

A BUSH, AP Gunn, BX Wong, T Johanssen, JC Griffith, CL Masters, KJ Barnham, JA Duce, RA Cherny

2016-01-01

High-resolution complementary chemical imaging of bio-elements in Caenorhabditis elegans

Dominic J Hare, Michael WM Jones, Verena C Wimmer, Nicole L Jenkins, Martin D de Jonge, Ashley I Bush, Gawain McColl

2016-01-01

Metal chaperones prevent zinc-mediated cognitive decline

Paul A Adlard, Jacqui Parncutt, Varsha Lal, Simon James, Dominic Hare, Philip Doble, David I Finkelstein, Ashley I Bush

2015-09-01

Neonatal iron supplementation potentiates oxidative stress, energetic dysfunction and neurodegeneration in the R6/2 mouse model of Huntington's disease

Kiersten L Berggren, Jianfang Chen, Julia Fox, Jonathan Miller, Lindsay Dodds, Bryan Dugas, Liset Vargas, Amber Lothian, Erin McAllum, Irene Volitakis, Blaine Roberts, Ashley I Bush, Jonathan H Fox

2015-04-01

Towards stage specific treatments: Effects of duration of illness on therapeutic response to adjunctive treatment with N-acetyl cysteine in schizophrenia

Marta Rapado-Castro, Michael Berk, Kamalesh Venugopal, Ashley I Bush, Seetal Dodd, Olivia M Dean

2015-03-03

Decreased Plasma Iron in Alzheimer's Disease Is Due to Transferrin Desatu ration

Dominic J Hare, James D Doecke, Noel G Faux, Alan Rembach, Irene Volitakis, Christopher J Fowler, Rudolf Grimm, Philip A Doble, Robert A Cherny, Colin L Masters, Ashley I Bush, Blame R Roberts

2015-03-01

Parkinson's Disease Iron Deposition Caused by Nitric Oxide-Induced Loss of beta-Amyloid Precursor Protein

Scott Ayton, Peng Lei, Dominic J Hare, James A Duce, Jessica L George, Paul A Adlard, Catriona McLean, Jack T Rogers, Robert A Cherny, David I Finkelstein, Ashley I Bush

2015-02-25

Follow-up plasma apolipoprotein E levels in the Australian Imaging, Biomarkers and Lifestyle Flagship Study of Ageing (AIBL) cohort

Veer B Gupta, Andrea C Wilson, Samantha Burnham, Eugene Hone, Steve Pedrini, Simon M Laws, Wei Ling Florence Lim, Alan Rembach, Stephanie Rainey-Smith, David Ames, Lynne Cobiac, S Lance Macaulay, Colin L Masters, Christopher C Rowe, Ashley I Bush, Ralph N Martins

2015-02-20

Biometals and Their Therapeutic Implications in Alzheimer's Disease

Scott Ayton, Peng Lei, Ashley I Bush

2015-01-01

Direct in vivo imaging of ferrous iron dyshomeostasis in ageing Caenorhabditis elegans

Simon A James, Blaine R Roberts, Dominic J Hare, Martin D de Jonge, Ian E Birchall, Nicole L Jenkins, Robert A Cherny, Ashley I Bush, Gawain McColl

2015-01-01

High Order W02-Reactive Stable Oligomers of Amyloid-beta are Produced in vivo and in vitro via Dialysis and Filtration of Synthetic Amyloid-beta Monomer

Elysia Robb, Keyla Perez, Lin W Hung, Colin L Masters, Kevin J Barnham, Robert A Cherny, Ashley I Bush, Paul A Adlard, David I Finkelstein

2015-01-01

Selenium, selenoproteins and neurodegenerative diseases

Barbara Rita Cardoso, Blaine R Roberts, Ashley I Bush, Dominic J Hare

2015-01-01

Traumatic brain injury induces elevation of Co in the human brain

Blaine R Roberts, Dominic J Hare, Catriona A McLean, Alison Conquest, Monica Lind, Qiao-Xin Li, Ashley I Bush, Colin L Masters, Maria-Christina Morganti-Kossmann, Tony Frugier

2015-01-01

Visualising mouse neuroanatomy and function by metal distribution using laser ablation-inductively coupled plasma-mass spectrometry imaging (vol 6, pg 5383, 2015)

Bence Paul, Dominic J Hare, David P Bishop, Chad Paton, Tran Nguyen Van, Nerida Cole, Megan M Niedzwiecki, Erica Andreozzi, Angela Vais, Jessica L Billings, Lisa Bray, Ashley I Bush, Gawain McColl, Blaine R Roberts, Paul A Adlard, David I Finkelstein, John Hellstrom, Janet M Hergt, Jon D Woodhead, Philip A Doble

2015-01-01

Copper-uptake is critical for the down regulation of synapsin and dynamin induced by neocuproine: modulation of synaptic activity in hippocampal neurons

Patricio A Castro, Alejandra Ramirez, Fernando J Sepulveda, Christian Peters, Humberto Fierro, Javier Waldron, Sandra Luza, Jorge Fuentealba, Francisco J Munoz, Giancarlo V De Ferrari, Ashley I Bush, Luis G Aguayo, Carlos M Opazo

2014-12-03

beta-Amyloid Precursor Protein Does Not Possess Ferroxidase Activity but Does Stabilize the Cell Surface Ferrous Iron Exporter Ferroportin

Bruce X Wong, Andrew Tsatsanis, Linh Q Lim, Paul A Adlard, Ashley I Bush, James A Duce

2014-12-02

A comparison of ceruloplasmin to biological polyanions in promoting the oxidation of Fe2 under physiologically relevant conditions

Bruce X Wong, Scott Ayton, Linh Q Lam, Peng Lei, Paul A Adlard, Ashley I Bush, James A Duce

2014-12-01

Altered selenium status in Huntington's disease: Neuroprotection by selenite in the N171-82Q mouse model

Zhen Lu, Eileen Marks, Jianfang Chen, Jenna Moline, Lorraine Barrows, Merl Raisbeck, Irene Volitakis, Robert A Cherny, Vanita Chopra, Ashley I Bush, Steven Hersch, Jonathan H Fox

2014-11-01

An anemia of Alzheimer's disease

NG Faux, A Rembach, J Wiley, KA Ellis, D Ames, CJ Fowler, RN Martins, KK Pertile, RL Rumble, B Trounson, CL Masters, AI Bush

2014-11-01

Influence of BDNF Val66Met on the relationship between physical activity and brain volume

Belinda M Brown, Pierrick Bourgeat, Jeremiah J Peiffer, Samantha Burnham, Simon M Laws, Stephanie R Rainey-Smith, David Bartres-Faz, Victor L Villemagne, Kevin Taddei, Alan Rembach, Ashley Bush, Kathryn A Ellis, S Lance Macaulay, Christopher C Rowe, David Ames, Colin L Masters, Paul Maruff, Ralph N Martins

2014-10-07

Dietary and lifestyle guidelines for the prevention of Alzheimer's disease

Neal D Barnard, Ashley I Bush, Antonia Ceccarelli, James Cooper, Celeste A de Jager, Kirk I Erickson, Gary Fraser, Shelli Kesler, Susan M Levin, Brendan Lucey, Martha Clare Morris, Rosanna Squitti

2014-09-01

An increased neutrophil-lymphocyte ratio in Alzheimer's disease is a function of age and is weakly correlated with neocortical amyloid accumulation

Alan Rembach, Andrew D Watt, William J Wilson, Stephanie Rainey-Smith, Kathryn A Ellis, Christopher C Rowe, Victor L Villemagne, S Lance Macaulay, Ashley I Bush, Ralph N Martins, David Ames, Colin L Masters, James D Doecke

2014-08-15

Motor and cognitive deficits in aged tau knockout mice in two background strains

Peng Lei, Scott Ayton, Steve Moon, Qihao Zhang, Irene Volitakis, David I Finkelstein, Ashley I Bush

2014-08-14

beta-amyloid in biological samples: not all A beta detection methods are created equal

Paul A Adlard, Qiao-Xin Li, Catriona McLean, Colin L Masters, Ashley I Bush, Michelle Fodero-Tavoletti, Victor Villemagne, Kevin J Barnham

2014-08-13

Iron accumulation confers neurotoxicity to a vulnerable population of nigral neurons: implications for Parkinson's disease

Scott Ayton, Peng Lei, Paul A Adlard, Irene Volitakis, Robert A Cherny, Ashley I Bush, David I Finkelstein

2014-07-10

Copper: from neurotransmission to neuroproteostasis

Carlos M Opazo, Marka A Greenough, Ashley I Bush

2014-07-03

Oral Treatment with Cu-II(atsm) Increases Mutant SOD1 In Vivo but Protects Motor Neurons and Improves the Phenotype of a Transgenic Mouse Model of Amyotrophic Lateral Sclerosis

Blaine R Roberts, Nastasia KH Lim, Erin J McAllum, Paul S Donnelly, Dominic J Hare, Philip A Doble, Bradley J Turner, Katherine A Price, Sin Chun Lim, Brett M Paterson, James L Hickey, Timothy W Rhoads, Jared R Williams, Katja M Kanninen, Lin W Hung, Jeffrey R Liddell, Alexandra Grubman, Jean-Francois Monty, Roxana M Llanos, David R Kramer

2014-06-04

RESPONSE TO COMMENT ON MOORE ET AL. Increased Risk of Cognitive Impairment in Patients With Diabetes Is Associated With Metformin. Diabetes Care 2013;36:2981-2987

Eileen M Moore, Alastair G Mander, David Ames, Mark A Kotowicz, Ross P Carne, Henry Brodaty, Michael Woodward, Kathryn A Ellis, Ashley I Bush, Noel G Faux, David A Watters

2014-06-01

Metals and cholesterol: two sides of the same coin in Alzheimer's disease pathology

Bruce X Wong, Ya Hui Hung, Ashley I Bush, James A Duce

2014-05-15

A blood-based predictor for neocortical A beta burden in Alzheimer's disease: results from the AIBL study

SC Burnham, NG Faux, W Wilson, SM Laws, D Ames, J Bedo, Ai Bush, JD Doecke, KA Ellis, R Head, G Jones, H Kiiveri, RN Martins, A Rembach, CC Rowe, O Salvado, SL Macaulay, CL Masters, VL Villemagne

2014-04-01

A novel approach to rapidly prevent age-related cognitive decline

Paul A Adlard, Amelia Sedjahtera, Lydia Gunawan, Lisa Bray, Dominic Hare, Jessica Lear, Philip Doble, Ashley I Bush, David I Finkelstein, Robert A Cherny

2014-04-01

Ceruloplasmin and beta-amyloid precursor protein confer neuroprotection in traumatic brain injury and lower neuronal iron

Scott Ayton, Moses Zhang, Blaine R Roberts, Linh Q Lam, Monica Lind, Catriona McLean, Ashley I Bush, Tony Frugier, Peter J Crack, James A Duce

2014-04-01

The effect of paraformaldehyde fixation and sucrose cryoprotection on metal concentration in murine neurological tissue

Dominic J Hare, Jessica L George, Lisa Bray, Irene Volitakis, Angela Vais, Timothy M Ryan, Robert A Cherny, Ashley I Bush, Colin L Masters, Paul A Adlard, Philip A Doble, David I Finkelstein

2014-03-01

Effect of BDNF Val66Met on Memory Decline and Hippocampal Atrophy in Prodromal Alzheimer's Disease: A Preliminary Study

Yen Ying Lim, Victor L Villemagne, Simon M Laws, David Ames, Robert H Pietrzak, Kathryn A Ellis, Karra Harrington, Pierrick Bourgeat, Ashley I Bush, Ralph N Martins, Colin L Masters, Christopher C Rowe, Paul Maruff

2014-01-27

Altered transition metal homeostasis in Niemann-Pick disease, type C1

Ya Hui Hung, Noel G Faux, David W Killilea, Nicole Yanjanin, Sally Firnkes, Irene Volitakis, George Ganio, Mark Walterfang, Caroline Hastings, Forbes D Porter, Daniel S Ory, Ashley I Bush

2014-01-01

An iron-dopamine index predicts risk of parkinsonian neurodegeneration in the substantia nigra pars compacta

Dominic J Hare, Peng Lei, Scott Ayton, Blaine R Roberts, Rudolf Grimm, Jessica L George, David P Bishop, Alison D Beavis, Sarah J Donovan, Gawain McColl, Irene Volitakis, Colin L Masters, Paul A Adlard, Robert A Cherny, Ashley I Bush, David I Finkelstein, Philip A Doble

2014-01-01

A review of β-amyloid neuroimaging in Alzheimer's disease

PA Adlard, BA Tran, DI Finkelstein, PM Desmond, LA Johnston, AI Bush, GF Egan

2014-01-01

Alzheimer's disease (AD) is the most common cause of dementia worldwide. As advancing age is the greatest risk factor for developi..

Associations between gonadotropins, testosterone and beta amyloid in men at risk of Alzheimer's disease

G Verdile, SM Laws, D Henley, D Ames, AI Bush, KA Ellis, NG Faux, VB Gupta, Q-X Li, CL Masters, KE Pike, CC Rowe, C Szoeke, K Taddei, VL Villemagne, RN Martins

2014-01-01

Biological metals and metal-targeting compounds in major neurodegenerative diseases

Kevin J Barnham, Ashley I Bush

2014-01-01

Changes in plasma amyloid beta in a longitudinal study of aging and Alzheimer's disease

Alan Rembach, Noel G Faux, Andrew D Watt, Kelly K Pertile, Rebecca L Rumble, Brett O Trounson, Christopher J Fowler, Blaine R Roberts, Keyla A Perez, Qiao-Xin Li, Simon M Laws, Kevin Taddei, Stephanie Rainey-Smith, Joanne S Robertson, Manu Vandijck, Hugo Vanderstichele, Kevin J Barnham, Kathryn A Ellis, Cassandra Szoeke, Lance Macaulay

2014-01-01

Meta-Analysis of Serum Non-Ceruloplasmin Copper in Alzheimer's Disease

Rosanna Squitti, Ilaria Simonelli, Mariacarla Ventriglia, Mariacristina Siotto, Patrizio Pasqualetti, Alan Rembach, James Doecke, Ashley I Bush

2014-01-01

Neuroprotective peptide-macrocycle conjugates reveal complex structure-activity relationships in their interactions with amyloid beta

Mingfeng Yu, Timothy M Ryan, Samantha Ellis, Ashley I Bush, James A Triccas, Peter J Rutledge, Matthew H Todd

2014-01-01

Plasma Amyloid-beta Levels are Significantly Associated with a Transition Toward Alzheimer's Disease as Measured by Cognitive Decline and Change in Neocortical Amyloid Burden

Alan Rembach, Andrew D Watt, William J Wilson, Victor L Villemagne, Samantha C Burnham, Kathryn A Ellis, Paul Maruff, David Ames, Christopher C Rowe, S Lance Macaulay, Ashley I Bush, Ralph N Martins, Colin L Masters, James D Doecke

2014-01-01

Quantitation and localization of intracellular redox active metals by X-ray fluorescence microscopy in cortical neurons derived from APP and APLP2 knockout tissue

Giuseppe D Ciccotosto, Simon A James, Matteo Altissimo, David Paterson, Stefan Vogt, Barry Lai, Martin D de Jonge, Daryl L Howard, Ashley I Bush, Roberto Cappai

2014-01-01

Clinical utility of the cogstate brief battery in identifying cognitive impairment in mild cognitive impairment and Alzheimer's disease.

P Maruff, YY Lim, D Darby, KA Ellis, RH Pietrzak, PJ Snyder, AI Bush, C Szoeke, A Schembri, D Ames, CL Masters

2013-12-23

Background: Previous studies have demonstrated the utility and sensitivity of the CogState Brief Battery (CBB) in detecting cognit..

BDNF Val66Met, A beta amyloid, and cognitive decline in preclinical Alzheimer's disease

Yen Ying Lim, Victor L Villemagne, Simon M Laws, David Ames, Robert H Pietrzak, Kathryn A Ellis, Karra D Harrington, Pierrick Bourgeat, Olivier Salvado, David Darby, Peter J Snyder, Ashley I Bush, Ralph N Martins, Colin L Masters, Christopher C Rowe, Pradeep J Nathan, Paul Maruff

2013-11-01

Increased risk of cognitive impairment in patients with diabetes is associated with metformin. Diabetes Care 2013;36:2981–2987.

EM Moore, AG Mander, D Ames, MA Kotowicz, RP Carne, H Brodaty, M Woodward, K Boundy, KA Ellis, AI Bush, NG Faux, R Martins, C Szoeke, C Rowe, DA Watters

2013-11-01

Metallostasis in Alzheimer's disease and Parkinson's disease

A Bush

2013-11-01

Iron Accumulates in Huntington's Disease Neurons: Protection by Deferoxamine

Jianfang Chen, Eileen Marks, Barry Lai, Zhaojie Zhang, James A Duce, Linh Q Lam, Irene Volitakis, Ashley I Bush, Steven Hersch, Jonathan H Fox

2013-10-11

Increased Risk of Cognitive Impairment in Patients With Diabetes Is Associated With Metformin

Eileen M Moore, Alastair G Mander, David Ames, Mark A Kotowicz, Ross P Carne, Henry Brodaty, Michael Woodward, Karyn Boundy, Kathryn A Ellis, Ashley I Bush, Noel G Faux, Ralph Martins, Cassandra Szoeke, Christopher Rowe, David A Watters

2013-10-01

Metallostasis in Alzheimer's disease

Scott Ayton, Peng Lei, Ashley I Bush

2013-09-01

Physical activity and amyloid-beta plasma and brain levels: results from the Australian Imaging, Biomarkers and Lifestyle Study of Ageing

BM Brown, JJ Peiffer, K Taddei, JK Lui, SM Laws, VB Gupta, T Taddei, VK Ward, MA Rodrigues, S Burnham, SR Rainey-Smith, VL Villemagne, A Bush, KA Ellis, CL Masters, D Ames, SL Macaulay, C Szoeke, CC Rowe, RN Martins

2013-08-01

Physical activity and amyloid-β plasma and brain levels: results from the Australian Imaging, Biomarkers and Lifestyle Study of Ageing.

BM Brown, JJ Peiffer, K Taddei, JK Lui, SM Laws, VB Gupta, T Taddei, VK Ward, MA Rodrigues, S Burnham, SR Rainey-Smith, VL Villemagne, A Bush, KA Ellis, CL Masters, D Ames, SL Macaulay, C Szoeke, CC Rowe, RN Martins

2013-08-01

Previous studies suggest physical activity improves cognition and lowers Alzheimer's disease (AD) risk. However, key AD pathogenic..

A delicate balance: Iron metabolism and diseases of the brain

Dominic Hare, Scott Ayton, Ashley Bush, Peng Lei

2013-07-18

Deserves a hearing? A case report of remitting tinnitus with N-acetyl cysteine

OM Dean, S Jeavons, GS Malhi, SM Cotton, M Tanious, K Kohlmann, K Hewitt, K Moss, C Allwang, I Schapkaitz, J Robbins, S Dodd, A Bush, M Berk

2013-07-01

Increasing Intracellular Bioavailable Copper Selectively Targets Prostate Cancer Cells

Michael A Cater, Helen B Pearson, Kamil Wolyniec, Paul Klaver, Maree Bilandzic, Brett M Paterson, Ashley I Bush, Patrick O Humbert, Sharon La Fontaine, Paul S Donnelly, Ygal Haupt

2013-07-01

A preliminary investigation on the efficacy of N-acetyl cysteine for mania or hypomania

Pedro Vieira da Silva Magalhaes, Olivia M Dean, Ashley I Bush, David L Copolov, Gin S Malhi, Kristy Kohlmann, Susan Jeavons, Ian Schapkaitz, Murray Anderson-Hunt, Michael Berk

2013-06-01

Three-Month Stability of the CogState Brief Battery in Healthy Older Adults, Mild Cognitive Impairment, and Alzheimer's Disease: Results from the Australian Imaging, Biomarkers, and Lifestyle-Rate of Change Substudy (AIBL-ROCS)

Yen Ying Lim, Judith Jaeger, Karra Harrington, Tim Ashwood, Kathryn A Ellis, Albrecht Stoeffler, Cassandra Szoeke, Rebecca Lachovitzki, Ralph N Martins, Victor L Villemagne, Ashley Bush, Colin L Masters, Christopher C Rowe, David Ames, David Darby, Paul Maruff

2013-06-01

The effect of dopamine on MPTP-induced rotarod disability

Scott Ayton, Jessica L George, Paul A Adlard, Ashley I Bush, Robert A Cherny, David I Finkelstein

2013-05-24

Cognitive Consequences of High A beta Amyloid in Mild Cognitive Impairment and Healthy Older Adults: Implications for Early Detection of Alzheimer's Disease

Yen Ying Lim, Kathryn A Ellis, Karra Harrington, Adrian Kamer, Robert H Pietrzak, Ashley I Bush, David Darby, Ralph N Martins, Colin L Masters, Christopher C Rowe, Greg Savage, Cassandra Szoeke, Victor L Villemagne, David Ames, Paul Maruff

2013-05-01

Ceruloplasmin dysfunction and therapeutic potential for Parkinson disease

Scott Ayton, Peng Lei, James A Duce, Bruce XW Wong, Amelia Sedjahtera, Paul A Adlard, Ashley I Bush, David I Finkelstein

2013-04-01

Metal dyshomeostasis and oxidative stress in Alzheimer's disease

Mark A Greenough, James Camakaris, Ashley I Bush

2013-04-01

Amine oxidase activity of beta-amyloid precursor protein modulates systemic and local catecholamine levels

JA Duce, S Ayton, AA Miller, A Tsatsanis, LQ Lam, L Leone, JE Corbin, H Butzkueven, TJ Kilpatrick, JT Rogers, KJ Barnham, DI Finkelstein, AI Bush

2013-02-01

Cognitive Decline in Adults with Amnestic Mild Cognitive Impairment and High Amyloid-beta: Prodromal Alzheimer's Disease?

Yen Ying Lim, Kathryn A Ellis, Karra Harrington, Robert H Pietrzak, Joanne Gale, David Ames, Ashley I Bush, David Darby, Ralph N Martins, Colin L Masters, Christopher C Rowe, Greg Savage, Cassandra Szoeke, Victor L Villemagne, Paul Maruff

2013-01-01

Decline in Cognitive Function over 18 Months in Healthy Older Adults with High Amyloid-beta

Kathryn A Ellis, Yen Ying Lim, Karra Harrington, David Ames, Ashley I Bush, David Darby, Ralph N Martins, Colin L Masters, Christopher C Rowe, Greg Savage, Cassandra Szoeke, Victor L Villemagne, Paul Maruff

2013-01-01

Decreased copper in Alzheimer's disease brain is predominantly in the soluble extractable fraction.

Alan Rembach, Dominic J Hare, Monica Lind, Christopher J Fowler, Robert A Cherny, Catriona McLean, Ashley I Bush, Colin L Masters, Blaine R Roberts

2013-01-01

Alzheimer's disease (AD) is the leading cause of dementia and represents a significant burden on the global economy and society. T..

Direct in vivo imaging of essential bioinorganics in Caenorhabditis elegans

Simon A James, Martin D de Jonge, Daryl L Howard, Ashley I Bush, David Paterson, Gawain McColl

2013-01-01

Links between copper and cholesterol in Alzheimer's disease

Ya Hui Hung, Ashley I Bush, Sharon La Fontaine

2013-01-01

Longitudinal Analysis of Serum Copper and Ceruloplasmin in Alzheimer's Disease

Alan Rembach, James D Doecke, Blaine R Roberts, Andrew D Watt, Noel G Faux, Irene Volitakis, Kelly K Pertile, Rebecca L Rumble, Brett O Trounson, Christopher J Fowler, William Wilson, Kathryn A Ellis, Ralph N Martins, Christopher C Rowe, Victor L Villemagne, David Ames, Colin L Masters, Ashley I Bush

2013-01-01

Profiling the iron, copper and zinc content in primary neuron and astrocyte cultures by rapid online quantitative size exclusion chromatography-inductively coupled plasma-mass spectrometry

Dominic J Hare, Alexandra Grubman, Timothy M Ryan, Amber Lothian, Jeffrey R Liddell, Rudolf Grimm, Toshiaki Matsuda, Philip A Doble, Robert A Cherny, Ashley I Bush, Anthony R White, Colin L Masters, Blaine R Roberts

2013-01-01

Rapid Decline in Episodic Memory in Healthy Older Adults with High Amyloid-beta

Yen Ying Lim, Robert H Pietrzak, Kathryn A Ellis, Judith Jaeger, Karra Harrington, Tim Ashwood, Cassandra Szoeke, Ralph N Martins, Ashley I Bush, Colin L Masters, Christopher C Rowe, Victor L Villemagne, David Ames, David Darby, Paul Maruff

2013-01-01

Zinc in Alzheimer's and Parkinson's Diseases

S AYTON, DI Finkelstein, RA Cherny, AI Bush, PA Adlard

2013-01-01

Characterization of the role of metallothionein-3 in an animal model of Alzheimer's disease

Yasmina Manso, Javier Carrasco, Gemma Comes, Gabriele Meloni, Paul A Adlard, Ashley I Bush, Milan Vasak, Juan Hidalgo

2012-11-01

Characterization of the role of the antioxidant proteins metallothioneins 1 and 2 in an animal model of Alzheimer's disease

Yasmina Manso, Javier Carrasco, Gemma Comes, Paul A Adlard, Ashley I Bush, Juan Hidalgo

2012-11-01

Blood-Based Protein Biomarkers for Diagnosis of Alzheimer Disease

James D Doecke, Simon M Laws, Noel G Faux, William Wilson, Samantha C Burnham, Chiou-Peng Lam, Alinda Mondal, Justin Bedo, Ashley I Bush, Belinda Brown, Karl De Ruyck, Kathryn A Ellis, Christopher Fowler, Veer B Gupta, Richard Head, S Lance Macaulay, Kelly Pertile, Christopher C Rowe, Alan Rembach, Mark Rodrigues

2012-10-01

Maintenance N-acetyl cysteine treatment for bipolar disorder: A double-blind randomized placebo controlled trial

Michael Berk, Olivia M Dean, Sue M Cotton, Clarissa S Gama, Flavio Kapczinski, Brisa Fernandes, Kristy Kohlmann, Susan Jeavons, Karen Hewitt, Kirsteen Moss, Christine Allwang, Ian Schapkaitz, Heidi Cobb, Ashley I Bush, Seetal Dodd, Gin S Malhi

2012-08-14

Alterations in Brain Transition Metals in Huntington Disease An Evolving and Intricate Story

H Diana Rosas, Y Iris Chen, Gheorghe Doros, David H Salat, Nan-kuei Chen, Ken K Kwong, Ashley Bush, Jonathan Fox, Steven M Hersch

2012-07-01

P2X7 Receptor-mediated Scavenger Activity of Mononuclear Phagocytes toward Non-opsonized Particles and Apoptotic Cells Is Inhibited by Serum Glycoproteins but Remains Active in Cerebrospinal Fluid

Ben J Gu, James A Duce, Valentina A Valova, Bruce Wong, Ashley I Bush, Steven Petrou, James S Wiley

2012-05-18

The hypoxia imaging agent Cu-II(atsm) is neuroprotective and improves motor and cognitive functions in multiple animal models of Parkinson's disease

Lin W Hung, Victor L Villemagne, Lesley Cheng, Nicki A Sherratt, Scott Ayton, Anthony R White, Peter J Crouch, SinChun Lim, Su Ling Leong, Simon Wilkins, Jessica George, Blaine R Roberts, Chi LL Pham, Xiang Liu, Francis CK Chiu, David M Shackleford, Andrew K Powell, Colin L Masters, Ashley I Bush, Graeme O'Keefe

2012-04-09

Metal chaperones: a holistic approach to the treatment of Alzheimer's disease.

Paul Anthony Adlard, Ashley Ian Bush

2012-03-02

As evidence for the role of metal ion dysregulation in the pathogenesis of multiple CNS disorders grows, it has become important t..

Caenorhabditis elegans Maintains Highly Compartmentalized Cellular Distribution of Metals and Steep Concentration Gradients of Manganese

Gawain McColl, Simon A James, Sheridan Mayo, Daryl L Howard, Christopher G Ryan, Robin Kirkham, Gareth F Moorhead, David Paterson, Martin D de Jonge, Ashley I Bush

2012-02-29

Tau deficiency induces parkinsonism with dementia by impairing APP-mediated iron export

Peng Lei, Scott Ayton, David I Finkelstein, Loredana Spoerri, Giuseppe D Ciccotosto, David K Wright, Bruce XW Wong, Paul A Adlard, Robert A Cherny, Linh Q Lam, Blaine R Roberts, Irene Volitakis, Gary F Egan, Catriona A McLean, Roberto Cappai, James A Duce, Ashley I Bush

2012-02-01

Elevated labile Cu is associated with oxidative pathology in Alzheimer disease

Simon A James, Irene Volitakis, Paul A Adlard, James A Duce, Colin L Masters, Robert A Cherny, Ashley I Bush

2012-01-15

The role of metallobiology and amyloid-ss peptides in Alzheimer's disease

Blaine R Roberts, Timothy M Ryan, Ashley I Bush, Colin L Masters, James A Duce

2012-01-01