A Randomised Clinical Trial Of Physical Activity To Delay The Progression Of Cerebrovascular Pathology

Abstract

The aim of this randomised clinical trial is to establish whether a 24 months physical activity (PA) program for older adults with memory problems can delay the progression of damage to the blood vessel system in the brain, measured on an MRI scan. It also will investigate whether cognition, mood, quality of life, functional level, fitness and biological markers will improve with the intervention. If successful this PA program could become part of clinical care for adults at risk of dementia.

Related publications (1)

Protocol for a randomized controlled trial evaluating the effect of physical activity on delaying the progression of white matter changes on MRI in older adults with memory complaints and mild cognitive impairment: The AIBL Active trial

Elizabeth V Cyarto, Nicola T Lautenschlager, Patricia M Desmond, David Ames, Cassandra Szoeke, Olivier Salvado, Matthew J Sharman, Kathryn A Ellis, Pramit M Phal, Colin L Masters, Christopher C Rowe, Ralph N Martins, Kay L Cox

2012-10-11