CENTRE FOR TRANSLATIONAL NEUROSCIENCE: A MODULAR PLATFORM FOR TRANSLATING DISCOVERY INTO HEALTH OUTCOMES
Grant number: 1001216 | Funding period: 2010 - 2016
Clinical Centre of Research Excellence in Translational Neuroscience will provide people, pathways and resources to create a novel platform to take the outputs of Neuroscience Discovery programs though to improved patient outcomes for common brain diseases. A critical role will be to train and equip the best and brightest of the next generation of researchers to undertake internationally competitive translational neuroscience research that makes a difference to the health of our community.
Related publications (11)
Defining secondary progressive multiple sclerosis
Johannes Lorscheider, Katherine Buzzard, Vilija Jokubaitis, Tim Spelman, Eva Havrdova, Dana Horakova, Maria Trojano, Guillermo Izquierdo, Marc Girard, Pierre Duquette, Alexandre Prat, Alessandra Lugaresi, Francois Grand'Maison, Pierre Grammond, Raymond Hupperts, Raed Alroughani, Patrizia Sola, Cavit Boz, Eugenio Pucci, Jeanette Lechner-Scott
The antiepileptic medications carbamazepine and phenytoin inhibit native sodium currents in murine osteoblasts
Sandra J Petty, Carol J Milligan, Marian Todaro, Kay L Richards, Pamuditha K Kularathna, Charles N Pagel, Chris R French, Elisa L Hill-Yardin, Terence J O'Brien, John D Wark, Eleanor J Mackie, Steven Petrou
OBJECTIVE: Fracture risk is a serious comorbidity in epilepsy and may relate to the use of antiepileptic drugs (AEDs). Many AEDs i..
A Method of Trigonometric Modelling of Seasonal Variation Demonstrated with Multiple Sclerosis Relapse Data
Tim Spelman, Orla Gray, Robyn Lucas, Helmut Butzkueven
This report describes a novel Stata-based application of trigonometric regression modelling to 55 years of multiple sclerosis rela..
Mind the gap: Multiple events and lengthy delays before presentation with a "first seizure"
Anna L Firkin, David JT Marco, Sibel Saya, Mark R Newton, Terence J O'Brien, Samuel F Berkovic, Anne M McIntosh
OBJECTIVE: Up to half of patients assessed for suspected new-onset epileptic seizures report previous undiagnosed events. This sug..
Single live cell TGF-beta signalling imaging: breast cancer cell motility and migration is driven by sub-populations of cells with dynamic TGF-beta-Smad3 activity
Rodney B Luwor, Dulani Hakmana, Josephine Iaria, Thao V Nheu, Richard J Simpson, Hong-Jian Zhu
BACKGROUND: Metastasis is a process where only a small subset of cells is capable of successfully migrating to and propagating at ..
Serum phosphorylated neurofilament-heavy chain levels in multiple sclerosis patients
MM Gresle, Y Liu, LF Dagley, J Haartsen, F Pearson, AW Purcell, L Laverick, A Petzold, RM Lucas, A Van der Walt, H Prime, DR Morris, BV Taylor, G Shaw, H Butzkueven
OBJECTIVES: We evaluated whether the measurement of serum phosphorylated neurofilament heavy chain (pNF-H) titre is likely to be a..
Weight and fat distribution in patients taking valproate: A valproate-discordant gender-matched twin and sibling pair study
Sandra J Petty, Susan Kantor, Kate M Lawrence, Samuel F Berkovic, Marnie Collins, Keith D Hill, Joanna Makovey, Philip N Sambrook, Terence J O'Brien, John D Wark
OBJECTIVES: Chronic treatment with valproate (VPA) is commonly associated with weight gain, which potentially has important health..
Symptomatic Intracranial Hemorrhage After Stroke Thrombolysis Comparison of Prediction Scores
Daniel Strbian, Patrik Michel, David J Seiffge, Jeffrey L Saver, Heikki Numminen, Atte Meretoja, Kei Murao, Bruno Weder, Nina Forss, Anna-Kaisa Parkkila, Ashraf Eskandari, Charlotte Cordonnier, Stephen M Davis, Stefan T Engelter, Turgut Tatlisumak
BACKGROUND AND PURPOSE: Several prognostic scores have been developed to predict the risk of symptomatic intracranial hemorrhage (..
Sex as a determinant of relapse incidence and progressive course of multiple sclerosis
Tomas Kalincik, Vino Vivek, Vilija Jokubaitis, Jeannette Lechner-Scott, Maria Trojano, Guillermo Izquierdo, Alessandra Lugaresi, Francois Grand'Maison, Raymond Hupperts, Celia Oreja-Guevara, Roberto Bergamaschi, Gerardo Iuliano, Raed Alroughani, Vincent Van Pesch, Maria Pia Amato, Mark Slee, Freek Verheul, Ricardo Fernandez-Bolanos, Marcela Fiol, Daniele La Spitaleri
The aim of this work was to evaluate sex differences in the incidence of multiple sclerosis relapses; assess the relationship betw..
Health-related quality of life as an independent predictor of long-term disability for patients with relapsingremitting multiple sclerosis
K Baumstarck, J Pelletier, H Butzkueven, O Fernandez, P Flachenecker, E Idiman, S Stecchi, M Boucekine, P Auquier
BACKGROUND AND PURPOSE: Predictive factors of long-term disability in patients with relapsing-remitting multiple sclerosis (RR-MS)..
A double-blind, randomized, controlled study of botulinum toxin type A in MS-related tremor
Anneke Van der Walt, Simon Sung, Timothy Spelman, Mark Marriott, Scott Kolbe, Peter Mitchell, Andrew Evans, Helmut Butzkueven
OBJECTIVE: To evaluate the safety and efficacy of botulinum toxin type A in disabling multiple sclerosis (MS)-related upper limb t..