TRAINING FELLOWSHIP - AUSTRALIAN BASED BIOMEDICAL FELLOWSHIP
Grant number: 602541 | Funding period: 2011 - 2014
Related publications (14)
Role of Plasmodium falciparum Protein GEXPO7 in Maurer's Cleft Morphology, Knob Architecture, and P. falciparum EMP1 Trafficking
Emma McHugh, Olivia MS Carmo, Adam Blanch, Oliver Looker, Boyin Liu, Snigdha Tiash, Dean Andrew, Steven Batinovic, Andy JY Low, Hyun-Jung Cho, Paul McMillan, Leann Tilley, Matthew WA Dixon
The malaria parasite Plasmodium falciparum traffics the virulence protein P. falciparum erythrocyte membrane protein 1 (PfEMP1) to..
The knob protein KAHRP assembles into a ring-shaped structure that underpins virulence complex assembly
Oliver Looker, Adam J Blanch, Boyin Liu, Juan Nunez-Iglesias, Paul J McMillan, Leann Tilley, Matthew WA Dixon
Plasmodium falciparum mediates adhesion of infected red blood cells (RBCs) to blood vessel walls by assembling a multi-protein com..
Disrupting assembly of the inner membrane complex blocks Plasmodium falciparum sexual stage development
Molly Parkyn Schneider, Boyin Liu, Philipp Glock, Annika Suttie, Emma McHugh, Dean Andrew, Steven Batinovic, Nicholas Williamson, Eric Hanssen, Paul McMillan, Marion Hliscs, Leann Tilley, Matthew WA Dixon
Transmission of malaria parasites relies on the formation of a specialized blood form called the gametocyte. Gametocytes of the hu..
A Plasmodium falciparum S33 proline aminopeptidase is associated with changes in erythrocyte deformability
Fabio L da Silva, Matthew WA Dixon, Colin M Stack, Franka Teuscher, Elena Taran, Malcolm K Jones, Erica Lovas, Leann Tilley, Christopher L Brown, Katharine R Trenholme, John P Dalton, Donald L Gardiner, Tina S Skinner-Adams
Infection with the apicomplexan parasite Plasmodium falciparum is a major cause of morbidity and mortality worldwide. One of the s..
Reversible host cell remodeling underpins deformability changes in malaria parasite sexual blood stages
Megan Dearnley, Trang Chu, Yao Zhang, Oliver Looker, Changjin Huang, Nectarios Klonis, Jeff Yeoman, Shannon Kenny, Mohit Arora, James M Osborne, Rajesh Chandramohanadas, Sulin Zhang, Matthew WA Dixon, Leann Tilley
The sexual blood stage of the human malaria parasite Plasmodium falciparum undergoes remarkable biophysical changes as it prepares..
Organization and function of an actin cytoskeleton in Plasmodium falciparum gametocytes
Marion Hliscs, Coralie Millet, Matthew W Dixon, Inga Siden-Kiamos, Paul McMillan, Leann Tilley
In preparation for transmission to its mosquito vector, Plasmodium falciparum, the most virulent of the human malaria parasites, a..
Red Blood Cells Polarize Green Laser Light Revealing Hemoglobin's Enhanced Non-Fundamental Raman Modes
Katarzyna M Marzec, David Perez-Guaita, Marleen de Veij, Don McNaughton, Malgorzata Baranska, Matthew WA Dixon, Leann Tilley, Bayden R Wood
In general, the first overtone modes produce weak bands that appear at approximately twice the wavenumber value of the fundamental..
A female gametocyte-specific ABC transporter plays a role in lipid metabolism in the malaria parasite
Phuong N Tran, Simon HJ Brown, Todd W Mitchell, Kai Matuschewski, Paul J McMillan, Kiaran Kirk, Matthew WA Dixon, Alexander G Maier
ATP-binding cassette (ABC) transporters serve a variety of physiological functions as well as play key roles in drug resistance. T..
Detection and Quantification of Early-Stage Malaria Parasites in Laboratory Infected Erythrocytes by Attenuated Total Reflectance Infrared Spectroscopy and Multivariate Analysis
Aazam Khoshmanesh, Matthew WA Dixon, Shannon Kenny, Leann Tilley, Don McNaughton, Bayden R Wood
New diagnostic modalities for malaria must have high sensitivity and be affordable to the developing world. We report on a method ..
Diagnosing malaria infected cells at the single cell level using focal plane array Fourier transform infrared imaging spectroscopy
Bayden R Wood, Keith R Bambery, Matthew WA Dixon, Leann Tilley, Michael J Nasse, Eric Mattson, Carol J Hirschmugl
New methods are needed to rapidly identify malaria parasites in blood smears. The coupling of a Focal Plane Array (FPA) infrared m..
The Plasmodium translocon of exported proteins (PTEX) component thioredoxin-2 is important for maintaining normal blood-stage growth
Kathryn Matthews, Ming Kalanon, Scott A Chisholm, Angelika Sturm, Christopher D Goodman, Matthew WA Dixon, Paul R Sanders, Thomas Nebl, Fiona Fraser, Silvia Haase, Geoffrey I McFadden, Paul R Gilson, Brendan S Crabb, Tania F deKoning-Ward
Plasmodium parasites remodel their vertebrate host cells by translocating hundreds of proteins across an encasing membrane into th..
Spatial and temporal mapping of the PfEMP1 export pathway in Plasmodium falciparum
Paul J McMillan, Coralie Millet, Steven Batinovic, Mauro Maiorca, Eric Hanssen, Shannon Kenny, Rebecca A Muhle, Martin Melcher, David A Fidock, Joseph D Smith, Matthew WA Dixon, Leann Tilley
The human malaria parasite, Plasmodium falciparum, modifies the red blood cells (RBCs) that it infects by exporting proteins to th..
Mitochondrial metabolism of sexual and asexual blood stages of the malaria parasite Plasmodium falciparum
James I MacRae, Matthew WA Dixon, Megan K Dearnley, Hwa H Chua, Jennifer M Chambers, Shannon Kenny, Iveta Bottova, Leann Tilley, Malcolm J McConville
BACKGROUND: The carbon metabolism of the blood stages of Plasmodium falciparum, comprising rapidly dividing asexual stages and non..
Temporal evaluation of commitment to sexual development in Plasmodium falciparum
Christopher L Peatey, Matthew WA Dixon, Donald L Gardiner, Katharine R Trenholme
BACKGROUND: The production of gametocytes is essential for transmission of malaria parasites from the mammalian host to the mosqui..