Stress-Induced Disease Risk For Pregnant Mothers Born Small

Grant number: 1025426 | Funding period: 2012 - 2014

Completed

Abstract

This proposal addresses the likelihood that mothers born small and exposed to stress during pregnancy will develop adverse physiological adaptations to pregnancy, slowing placental and fetal growth, programming intergenerational disease and compromising maternal health later in life. The outcomes from our human and rat studies will enable development of diagnostic tests to identify pregnancies at greater risk and lead to therapies to reduce adverse intergenerational and long-term health effects.

Researchers