What Causes Increased Release Of Noradrenaline During Heart Failure

Grant number: 1020783 | Funding period: 2012 - 2015

Completed

Abstract

Heart failure is associated with increased release of the neurotransmitter noradrenaline from sympathetic nerves to the heart and the kidney. The raised levels of this neurotransmitter in the heart and the kidney are harmful and lead to reduced survival in heart failure patients. This project will increase our understanding of the mechanisms that control noradrenaline release and may lead to better treatment paradigms to target the detrimental increase in release in heart failure.

Researchers