Regulation of cellular senescence

Grant number: 1026990 | Funding period: 2012 - 2014

Completed

Abstract

Cancer is constantly being suppressed in our bodies by a process that stops damaged cells from growing: 'senescence'. The mechanism that translates the damage stimuli into this state of permanent cell arrest is only partially known. We have identified a protein that appears to drive this restraint. The possibility of manipulating this process to prevent and cure cancer makes it in important target to study.

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Researchers