Glia In Remodelling The Inner Retina

Grant number: 1021042 | Funding period: 2012 - 2015

Completed

Abstract

The development of treatments that restore vision assumes that the output neurons of the retina remain intact. Yet, there is now considerable evidence that the neurons that signal from the retina to the brain are altered in those that have degenerative diseases of the retina. Here, we will examine the cause of these cellular changes in an animal model and seek to prevent the loss of output neurons. This information is crucial for the development of treatments that seeks to restore vision.