AT1A receptor in hypertension
Grant number: 1029396 | Funding period: 2012 - 2015
Angiotensin is important for normal regulation of blood pressure but is also involved in cardiovascular diseases. Interruption of angiotensin’s actions is a common treatment of these diseases. Functional deletion of angiotensin receptors decreases blood pressure. Surprisingly the site(s) in the body responsible for this decrease are not known. We will examine the role of angiotensin receptors in the brain in the control of blood pressure in health and in cardiovascular disease.
Related publications (3)
Stimulation of Angiotensin Type 1A Receptors on Catecholaminergic Cells Contributes to Angiotensin-Dependent Hypertension
Nikola Jancovski, Jaspreet K Bassi, David A Carter, Yan-Ting Choong, Angela Connelly, Nguyen Thu-Phuc, Daian Chen, Elena V Lukoshkova, Clement Menuet, Geoffrey A Head, Andrew M Allen