Role Of T Cell In Chronic Periodontitis

Grant number: 1029878 | Funding period: 2012 - 2014

Completed

Abstract

Particular immune cell populations (innate T cells), have a critical role in immunity. These cells are stimulated by bacterial cell wall components and are one of the first cells to appear after infection. We have shown that these innate T cells are stimulated by oral bacteria that cause the disease chronic periodontitis. This project will investigate how these innate T cells affect bacterial induced periodontitis and what role they play in disease outcomes.