Clonal Adaptation Of Human Melanoma In Response To Treatment; Implications For Acquired Therapy Resistance

Grant number: 1035298 | Funding period: 2013 - 2017

Completed

Abstract

Melanoma is the 4th most common cancer diagnosed in Australia. Advanced melanoma frequently spreads to other organs and can acquire resistance to anti-melanoma treatments, making it fundamentally incurable. I am focused on investigating the mechanisms underlying melanoma disease progression. I will achieve this by comparing the biological nature of melanoma cells at different stages of disease and therapy-resistance to identify new targets for the more effective treatment of patients with melanoma.