Investigation of Novel Therapeutic Targets for the Treatment of Drug Addiction

Grant number: 1037080 | Funding period: 2012 - 2018

Completed

Abstract

Drug abuse remains one of the world’s leading health care problems and the current drugs available to treat drug addiction are largely ineffective. This project aims to investigate the potential of a novel therapeutic target for the treatment of drug addiction with has the capacity for substantially reduced off-target effects.

Related publications (2)

The mGlu5 receptor regulates extinction of cocaine-driven behaviours

MK Bird, P Lohmann, B West, RM Brown, J Kirchhoff, CR Raymond, AJ Lawrence

2014-04-01

Background: There is extensive evidence implicating the metabotropic glutamate 5 (mGlu5) receptor in aspects of addiction-related..

Investigation of the neuroanatomical substrates of reward seeking following protracted abstinence in mice

HB Madsen, RM Brown, JL Short, AJ Lawrence

2012-05-01

Persistent vulnerability to relapse represents a major challenge in the treatment of drug addiction. The brain circuitry that unde..

University of Melbourne Researchers

Robyn M Brown

Andrew Lawrence