Grant number: 1020401 | Funding period: 2012 - 2016
My research focuses on understanding pathobiological mechanisms in acute and chronic neurodegenerative conditions such as stroke and Parkinson’s disease which have large burdens on the community through health care costs and on families because of the lack of effective treatments. An improved understanding of how brain cells die and of how the most abundant brain cell, the astrocyte, can be engineered to be a resource for regenerative medicine offer promise for improved clinical management.
Related publications (11)
Galactose-functionalised PCL nanofibre scaffolds to attenuate inflammatory action of astrocytes in vitro and in vivo
Francesca L Maclean, Chew L Lau, Sam Ozergun, Ross D O'Shea, Cecilia Cederfur, Jason Wang, Kevin E Healy, Frederick R Walker, Doris Tomas, Malcolm K Horne, Philip M Beart, David R Nisbet
Gene profiling identifies commonalities in neuronal pathways in excitotoxicity: Evidence favouring cell cycle re-activation in concert with oxidative stress
Minghui Jessica Chen, Jian Ming Jeremy Ng, Zhao Feng Peng, Jayapal Manikandan, Yann Wan Yap, Roxana M Llanos, Philip M Beart, Nam Sang Cheung