STEM CELLS AUSTRALIA
Grant number: SR1101002 | Funding period: 2011 - 2019
Despite progress in stem cell research, scientists do not understand how stem cells “decide” what to become. Stem Cells Australia will draw upon strengths within Australia’s premier stem cell research universities and institutes. This collaboration between leading bioengineering, nanotechnology, stem cell and advanced molecular analysis experts, will fast-track efforts to deliver a fundamental understanding of the mechanisms of stem cell regulation and differentiation, and the ability to control and influence this process. Stem Cells Australia will deliver new methods for stem cell propagation and manipulation, new translational technologies for therapeutic applications, and will prepare Aus..View full description
Related publications (4)
Integrating single-cell genomics pipelines to discover mechanisms of stem cell differentiation
Sophie Shen, Yuliangzi Sun, Maika Matsumoto, Woo Jun Shim, Enakshi Sinniah, Sean B Wilson, Tessa Werner, Zhixuan Wu, Stephen T Bradford, James Hudson, Melissa H Little, Joseph Powell, Quan Nguyen, Nathan J Palpant
Pluripotent stem cells underpin a growing sector that leverages their differentiation potential for research, industry, and clinic..
Single cell eQTL analysis identifies cell type-specific genetic control of gene expression in fibroblasts and reprogrammed induced pluripotent stem cells
Drew Neavin, Quan Nguyen, Maciej S Daniszewski, Helena H Liang, Han Sheng Chiu, Yong Kiat Wee, Anne Senabouth, Samuel W Lukowski, Duncan E Crombie, Grace E Lidgerwood, Damian Hernandez, James C Vickers, Anthony L Cook, Nathan J Palpant, Alice Pebay, Alex W Hewitt, Joseph E Powell
BACKGROUND: The discovery that somatic cells can be reprogrammed to induced pluripotent stem cells (iPSCs) has provided a foundati..
Shared activity patterns arising at genetic susceptibility loci reveal underlying genomic and cellular architecture of human disease
J Kenneth Baillie, Andrew Bretherick, Christopher S Haley, Sara Clohisey, Alan Grays, Lucile PA Neyton, Jeffrey Barrett, Eli A Stahl, Albert Tenesa, Robin Andersson, J Ben Brown, Geoffrey J Faulkner, Marina Lizio, Ulf Schaefer, Carsten Daub, Masayoshi Itoh, Naoto Kondo, Timo Lassmann, Jun Kawai, Damian Mole
Genetic variants underlying complex traits, including disease susceptibility, are enriched within the transcriptional regulatory e..
Dynamic interplay of innate and adaptive immunity during sterile retinal inflammation: Insights from the transcriptome
Riccardo Natoli, Elizabeth Mason, Haihan Jiao, Aaron Chuah, Hardip Patel, Nilisha Fernando, Krisztina Valter, Christine Wells, Jan Provis, Matt Rutar
The pathogenesis of many retinal degenerations, such as age-related macular degeneration (AMD), is punctuated by an ill-defined ne..