Elucidating the neural pathways and genetic basis of speech

Grant number: DP120100285 | Funding period: 2012 - 2016

Completed

Abstract

The project will elucidate the biological basis of speech, a unique feature of the human condition. The project will do this by i) discovering genes associated with speech disorder and ii) defining the neural pathways associated with speech production. This study will address critical questions regarding gene, brain and behaviour relationships in speech.

Related publications (6)

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Dorsal language stream anomalies in an inherited speech disorder

Frederique J Liegeois, Samantha J Turner, Angela Mayes, Alexandra F Bonthrone, Amber Boys, Libby Smith, Bronwyn Parry-Fielder, Simone Mandelstam, Megan Spencer-Smith, Melanie Bahlo, Tom S Scerri, Michael S Hildebrand, Ingrid E Scheffer, Alan Connelly, Angela T Morgan

2019-04-01

Speech disorders are highly prevalent in the preschool years, but frequently resolve. The neurobiological basis of the most persis..

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Early neuroimaging markers of FOXP2 intragenic deletion

Frederique J Liegeois, Michael S Hildebrand, Alexandra Bonthrone, Samantha J Turner, Ingrid E Scheffer, Melanie Bahlo, Alan Connelly, Angela T Morgan

2016-10-13

FOXP2 is the major gene associated with severe, persistent, developmental speech and language disorders. While studies in the orig..

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Neural correlates of childhood language disorder: a systematic review

Angela K Mayes, Sheena Reilly, Angela T Morgan

2015-08-01

AIM: The neurobiological contributions of childhood language disorder are not well understood. Yet there is increasing evidence th..

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Innovative assessment reveals speech production and language comprehension are dissociable skills in severe cerebral palsy

Angela T Morgan

2015-03-01

This commentary is on the original article by Geytenbeek et al. on pages 294-300 of this issue.

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Small Intragenic Deletion in FOXP2 Associated With Childhood Apraxia of Speech and Dysarthria

Samantha J Turner, Michael S Hildebrand, Susan Block, John Damiano, Michael Fahey, Sheena Reilly, Melanie Bahlo, Ingrid E Scheffer, Angela T Morgan

2013-09-01

Relatively little is known about the neurobiological basis of speech disorders although genetic determinants are increasingly reco..

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Speech-language pathology insights into genetics and neuroscience: Beyond surface behaviour

Angela Morgan

2013-06-01

For almost a century, speech-language pathologists (SLPs) have worked at refining communication disorder phenotypes. Yet a hundred..

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