Elucidating the neural pathways and genetic basis of speech

Severe childhood speech disorder: Gene discovery highlights transcriptional dysregulation

Michael S Hildebrand, Victoria E Jackson, Thomas S Scerri, Olivia Van Reyk, Matthew Coleman, Ruth O Braden, Samantha Turner, Kristin A Rigbye, Amber Boys, Sarah Barton, Richard Webster, Michael Fahey, Kerryn Saunders, Bronwyn Parry-Fielder, Georgia Paxton, Michael Hayman, David Coman, Himanshu Goel, Anne Baxter, Alan Ma

2020-05-19

OBJECTIVE: Determining the genetic basis of speech disorders provides insight into the neurobiology of human communication. Despit..

Looking to the Future: Speech, Language, and Academic Outcomes in an Adolescent with Childhood Apraxia of Speech

Samantha J Turner, Adam P Vogel, Bronwyn Parry-Fielder, Rhonda Campbell, Ingrid E Scheffer, Angela T Morgan

2019-10-01

OBJECTIVE: The clinical course of childhood apraxia of speech (CAS) is poorly understood. Of the few longitudinal studies in the f..

Dorsal language stream anomalies in an inherited speech disorder

Frederique J Liegeois, Samantha J Turner, Angela Mayes, Alexandra F Bonthrone, Amber Boys, Libby Smith, Bronwyn Parry-Fielder, Simone Mandelstam, Megan Spencer-Smith, Melanie Bahlo, Tom S Scerri, Michael S Hildebrand, Ingrid E Scheffer, Alan Connelly, Angela T Morgan

2019-04-01

Speech disorders are highly prevalent in the preschool years, but frequently resolve. The neurobiological basis of the most persis..

Dysarthria and broader motor speech deficits in Dravet syndrome

Samantha J Turner, Amy Brown, Marta Arpone, Vicki Anderson, Angela T Morgan, Ingrid E Scheffer

2017-02-21

OBJECTIVE: To analyze the oral motor, speech, and language phenotype in 20 children and adults with Dravet syndrome (DS) associate..

Early neuroimaging markers of FOXP2 intragenic deletion

Frederique J Liegeois, Michael S Hildebrand, Alexandra Bonthrone, Samantha J Turner, Ingrid E Scheffer, Melanie Bahlo, Alan Connelly, Angela T Morgan

2016-10-13

FOXP2 is the major gene associated with severe, persistent, developmental speech and language disorders. While studies in the orig..

Neural correlates of childhood language disorder: a systematic review

Angela K Mayes, Sheena Reilly, Angela T Morgan

2015-08-01

AIM: The neurobiological contributions of childhood language disorder are not well understood. Yet there is increasing evidence th..

Innovative assessment reveals speech production and language comprehension are dissociable skills in severe cerebral palsy

Angela T Morgan

2015-03-01

This commentary is on the original article by Geytenbeek et al. on pages 294-300 of this issue.

GRIN2A An aptly named gene for speech dysfunction

Samantha J Turner, Angela K Mayes, Andrea Verhoeven, Simone A Mandelstam, Angela T Morgan, Ingrid E Scheffer

2015-02-10

OBJECTIVE: To delineate the specific speech deficits in individuals with epilepsy-aphasia syndromes associated with mutations in t..

Small Intragenic Deletion in FOXP2 Associated With Childhood Apraxia of Speech and Dysarthria

Samantha J Turner, Michael S Hildebrand, Susan Block, John Damiano, Michael Fahey, Sheena Reilly, Melanie Bahlo, Ingrid E Scheffer, Angela T Morgan

2013-09-01

Relatively little is known about the neurobiological basis of speech disorders although genetic determinants are increasingly reco..

Speech-language pathology insights into genetics and neuroscience: Beyond surface behaviour

Angela Morgan

2013-06-01

For almost a century, speech-language pathologists (SLPs) have worked at refining communication disorder phenotypes. Yet a hundred..