Dissecting catalysis and inhibition of a unique endo-acting mannose-processing glycosidase

Grant number: DP120101396 | Funding period: 2012 - 2015

Completed

Abstract

Defects in the attachment of carbohydrates to proteins are a hallmark of diseases such as cancer and viral infection. This project will dissect the molecular details of the bond-making and breaking steps that occur during the synthesis of glycoproteins assisting in the development of innovative new drugs.

Related publications (7)

University of Melbourne Researchers