Towards the development of orally active antimicrobial peptides with distinctive mode of action
Grant number: DP120101963 | Funding period: 2012 - 2014
This project aims to design and develop novel antibacterial compounds to address one of humankind's greatest health concerns, that of antibacterial resistance. These will be further modified to make them orally available, thus enhancing their therapeutic and clinical potential.
Related publications (2)
Rapid systemic and local treatments with the antibacterial peptide dimer A3-APO and its monomeric metabolite eliminate bacteria and reduce inflammation in intradermal lesions infected with Propionibacterium acnes and meticillin-resistant Staphylococcus aureus
Eszter Ostorhazi, Elvira Voros, Eva Nemes-Nikodem, Dora Pinter, Palma Sillo, Balazs Mayer, John D Wade, Laszlo Otvos