Genetic and Environmental Determinants of Brain Networks in Ageing

Brain-age prediction: Systematic evaluation of site effects, and sample age range and size

Y Yu, HQ Cui, SS Haas, F New, N Sanford, K Yu, D Zhan, G Yang, JH Gao, D Wei, J Qiu, N Banaj, DI Boomsma, A Breier, H Brodaty, RL Buckner, JK Buitelaar, DM Cannon, X Caseras, VP Clark

2024-07-15

Structural neuroimaging data have been used to compute an estimate of the biological age of the brain (brain-age) which has been a..

Heritability of Gene Expression Measured from Peripheral Blood in Older Adults

SC Kanchibhotla, KA Mather, NJ Armstrong, LG Ciobanu, BT Baune, VS Catts, PR Schofield, JN Trollor, D Ames, PS Sachdev, A Thalamuthu

2024-04-01

The contributions of genetic variation and the environment to gene expression may change across the lifespan. However, few studies..

Genetic and environmental influences on fruit and vegetable consumption and depression in older adults

Annabel PP Matison, Anbupalam Thalamuthu, Victoria MM Flood, Julian NN Trollor, Vibeke SS Catts, Margaret JJ Wright, David Ames, Henry Brodaty, Perminder SS Sachdev, Simone Reppermund, Karen AA Mather

2023-02-03

BACKGROUND: Prior work suggests that higher fruit and vegetable consumption may protect against depression in older adults. Better..

High polygenic risk score for exceptional longevity is associated with a healthy metabolic profile

M Revelas, A Thalamuthu, A Zettergren, C Oldmeadow, J Najar, NM Seidu, NJ Armstrong, C Riveros, JB Kwok, PR Schofield, JN Trollor, M Waern, MJ Wright, H Zetterberg, D Ames, K Belnnow, H Brodaty, RJ Scott, I Skoog, JR Attia

2023-02-01

Healthy metabolic measures in humans are associated with longevity. Dysregulation leads to metabolic syndrome (MetS) and negative ..

Investigating Olfactory Gene Variation and Odour Identification in Older Adults

Siddharth Raj, Anbupalam Thalamuthu, Nicola J Armstrong, Margaret J Wright, John B Kwok, Julian N Trollor, David Ames, Peter R Schofield, Henry Brodaty, Perminder S Sachdev, Karen A Mather

2021-05-01

Ageing is associated with a decrease in odour identification. Additionally, deficits in olfaction have been linked to age-related ..