How Do Anti-Epileptic Drugs Work?

Spatiotemporal patterns of high-frequency activity (80-170 Hz) in long-term intracranial EEG

Zhuying Chen, David Grayden, Anthony Burkitt, Udaya Seneviratne, Wendyl D’Souza, Chris French, Philippa Karoly, Katrina Dell, Mark Cook, Matias Maturana

2020-03-26

<h4>Objective</h4> To assess the variability in the rates and locations of high-frequency activity (HFA) and epileptiform spikes a..

Local anesthetic and antiepileptic drug access and binding to a bacterial voltage-gated sodium channel

Celine Boiteux, Igor Vorobyov, Robert J French, Christopher French, Vladimir Yarov-Yarovoy, Toby W Allen

2014-09-09

Voltage-gated sodium (Nav) channels are important targets in the treatment of a range of pathologies. Bacterial channels, for whic..