Tracking the Cellular Responses to HTT Aggregation With New Enabling Toolkits

N-terminal fragments of huntingtin longer than residue 170 form visible aggregates independently to polyglutamine expansion

MZ Chen, SA Mok, AR Ormsby, PJ Muchowski, DM Hatters

2017-01-01

Background: A hallmark of Huntington's disease is the progressive aggregation of full length and N-terminal fragments of polygluta..