Harnessing the 'omics revolution to investigate drug response and resistance mechanisms in Giardia duodenalis
Grant number: LP120200122 | Funding period: 2012 - 2017
This international research project will harness cutting-edge technologies to explore how Giardia, a major global cause of diarrhoeal illness in humans, responds to and becomes resistant to key anti-giardial drugs, providing valuable information for drug preservation and development.
Related publications (2)
Transcriptomics Indicates Active and Passive Metronidazole Resistance Mechanisms in Three Seminal Giardia Lines
Brendan RE Ansell, Louise Baker, Samantha J Emery, Malcolm J McConville, Staffan G Svard, Robin B Gasser, Aaron R Jex
Giardia duodenalis is an intestinal parasite that causes 200-300 million episodes of diarrhoea annually. Metronidazole (Mtz) is a ..
Divergent Transcriptional Responses to Physiological and Xenobiotic Stress in Giardia duodenalis
Brendan RE Ansell, Malcolm J McConville, Louise Baker, Pasi K Korhonen, Samantha J Emery, Staffan G Svard, Robin B Gasser, Aaron R Jex
Understanding how parasites respond to stress can help to identify essential biological processes. Giardia duodenalis is a parasit..