A RANDOMISED CLINICAL TRIAL OF PHYSICAL ACTIVITY TO DELAY THE PROGRESSION OF CEREBROVASCULAR PATHOLOGY
Grant number: 1005942 | Funding period: 2011 - 2015
The aim of this randomised clinical trial is to establish whether a 24 months physical activity (PA) program for older adults with memory problems can delay the progression of damage to the blood vessel system in the brain, measured on an MRI scan. It also will investigate whether cognition, mood, quality of life, functional level, fitness and biological markers will improve with the intervention. If successful this PA program could become part of clinical care for adults at risk of dementia.
Related publications (5)
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The Alzheimer's Association International Conference held its sixth Satellite Symposium in Sydney, Australia in 2019, highlighting..
A Randomized Controlled Trial of Adherence to a 24-Month Home-Based Physical Activity Program and the Health Benefits for Older Adults at Risk of Alzheimer's Disease: The AIBL Active-Study
Kay L Cox, Elizabeth Cyarto, Kathryn A Ellis, David Ames, Patricia Desmond, Pramit Phal, Matthew J Sharman, Cassandra Szoeke, Christopher C Rowe, Colin L Masters, Emily You, Sally Burrows, Michelle MY Lai, Nicola T Lautenschlager
BACKGROUND: Previous studies have demonstrated that physical activity (PA) interventions can improve physical and cognitive outcom..
Protocol for a randomized controlled trial evaluating the effect of physical activity on delaying the progression of white matter changes on MRI in older adults with memory complaints and mild cognitive impairment: The AIBL Active trial
Elizabeth V Cyarto, Nicola T Lautenschlager, Patricia M Desmond, David Ames, Cassandra Szoeke, Olivier Salvado, Matthew J Sharman, Kathryn A Ellis, Pramit M Phal, Colin L Masters, Christopher C Rowe, Ralph N Martins, Kay L Cox
BACKGROUND: Older adults free of dementia but with subjective memory complaints (SMC) or mild cognitive impairment (MCI) are consi..