Targetting deregulated signalling pathways in high-grade serous ovarian cancer: Defining therapeutic response and mechanisms of resistance

Grant number: 1043884 | Funding period: 2013 - 2015



Ovarian cancer is the major cause of death from gynaecological cancer. Most patients present with advanced disease and die of their cancer. This proposal aims to use new research detailing the common genetic changes in tumour samples and our extensive panel of ovarian cancer cell lines to identify new treatment options for specific types of ovarian cancer. We expect this will result in clinical trials of therapies selected based on the characteristics of an individual patient’s disease.

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University of Melbourne Researchers