In vivo tau imaging in Alzheimer's disease and other dementias

Grant number: 1044361 | Funding period: 2013 - 2015

Completed

Abstract

Alteration of the normal protein tau leads to its deposition inside the brain cells leading to their death. These deposits have been well characterized and they are associated with cognitive impairment. We propose to study tau deposits in vivo in humans using positron emission tomography (PET) and assess its association with cognition and other signs of neurodegeneration

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