Avert: A Large, International, Randomised Controlled Trial Testing Efficacy And Cost Effectiveness Of Early And Frequent Mobilisation After Stroke

Grant number: 1041401 | Funding period: 2013 - 2016

Completed

Abstract

AVERT is a large, international clinical trial that tests whether introducing early and frequent exercise helps reduce the unacceptably high burden of death and disability associated with stroke. We are also testing if the intervention is cost effective. This trial will provide reliable evidence to guide clinical practice. If positive, broad implementation in both developed and developing countries is likely, thus helping to reduce the global burden of stroke related death and disability.

Related publications (6)

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Prespecified dose-response analysis for A Very Early Rehabilitation Trial (AVERT)

Julie Bernhardt, Leonid Churilov, Fiona Ellery, Janice Collier, Jan Chamberlain, Peter Langhorne, Richard I Lindley, Marj Moodie, Helen Dewey, Amanda G Thrift, Geoff Donnan

2016-06-07

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Economic Evaluation Plan (EEP) for A Very Early Rehabilitation Trial (AVERT): An international trial to compare the costs and cost-effectiveness of commencing out of bed standing and walking training (very early mobilization) within 24h of stroke onset with usual stroke unit care

Lauren Sheppard, Helen Dewey, Julie Bernhardt, Janice M Collier, Fiona Ellery, Leonid Churilov, Kiu Tay-Teo, Olivia Wu, Marj Moodie

2016-06-01

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Implementing a complex rehabilitation intervention in a stroke trial: a qualitative process evaluation of AVERT

Julie A Luker, Louise E Craig, Leanne Bennett, Fiona Ellery, Peter Langhorne, Olivia Wu, Julie Bernhardt

2016-05-10

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CHRISTMAS 2015: PROFESSIONAL CONSIDERATIONS AVERT(2) (a very early rehabilitation trial, a very effective reproductive trigger): retrospective observational analysis of the number of babies born to trial staff

Julie Bernhardt, Richard I Lindley, Erin Lalor, Fiona Ellery, Jan Chamberlain, John Van Holsteyn, Janice M Collier, Helen M Dewey, Brooke Parsons, Marjory Moodie, Sheila Lennon, Geoffrey A Donnan, Amanda G Thrift, Leonid Churilov, Peter Langhorne

2015-12-11

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Efficacy and safety of very early mobilisation within 24 h of stroke onset (AVERT): a randomised controlled trial

Julie Bernhardt, Peter Langhorne, Richard I Lindley, Amanda G Thrift, Fiona Ellery, Janice Collier, Leonid Churilov, Marjory Moodie, Helen Dewey, Geoffrey Donnan

2015-07-04

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Exploring threats to generalisability in a large international rehabilitation trial (AVERT)

Julie Bernhardt, Audrey Raffelt, Leonid Churilov, Richard I Lindley, Sally Speare, Jacqueline Ancliffe, Md Ali Katijjahbe, Shahul Hameed, Sheila Lennon, Anna McRae, Dawn Tan, Jan Quiney, Hannah C Williamson, Janice Collier, Helen M Dewey, Geoffrey A Donnan, Peter Langhorne, Amanda G Thrift

2015-01-01