Improving outcomes for women diagnosed with mucinous ovarian cancer

Grant number: 1045783 | Funding period: 2013 - 2016

Completed

Abstract

Mucinous ovarian cancer (MOC) is different from other ovarian cancers but few studies have characterized the genetic changes specific to this subtype. It is often confused with metastases from other organs and does not respond well to standard ovarian cancer therapies. If MOC is more similar to mucinous cancers from other organs than other ovarian cancers, it may be better treated with chemotherapeutics that show success with other mucinous tumours.

Related publications (6)

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Options for the Treatment of Mucinous Ovarian Carcinoma

Olivia Craig, Carolina Salazar, Kylie L Gorringe

2021-12-01

Complete surgical resection is the gold-standard treatment for all mucinous ovarian carcinoma (MOC) cases. Advanced-stage disease ..

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The Protein Landscape of Mucinous Ovarian Cancer: Towards a Theranostic

Arkan Youssef, Mohammad B Haskali, Kylie L Gorringe

2021-11-01

MOC is a rare histotype of epithelial ovarian cancer, and current management options are inadequate for the treatment of late stag..

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Therapeutic options for mucinous ovarian carcinoma

Kylie L Gorringe, Dane Cheasley, Matthew J Wakefield, Georgina L Ryland, Prue E Allan, Kathryn Alsop, Kaushalya C Amarasinghe, Sumitra Ananda, David DL Bowtell, Michael Christie, Yoke-Eng Chiew, Michael Churchman, Anna DeFazio, Sian Fereday, C Blake Gilks, Charlie Gourley, Alison M Hadley, Joy Hendley, Sally M Hunter, Scott H Kaufmann

2020-03-01

OBJECTIVE: Mucinous ovarian carcinoma (MOC) is an uncommon ovarian cancer histotype that responds poorly to conventional chemother..

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The molecular origin and taxonomy of mucinous ovarian carcinoma

Dane Cheasley, Matthew J Wakefield, Georgina L Ryland, Prue E Allan, Kathryn Alsop, Kaushalya C Amarasinghe, Sumitra Ananda, Michael S Anglesio, George Au-Yeung, Maret Bohm, David Dl Bowtell, Alison Brand, Georgia Chenevix-Trench, Michael Christie, Yoke-Eng Chiew, Michael Churchman, Anna DeFazio, Renee Demeo, Rhiannon Dudley, Nicole Fairweather

2019-09-02

Mucinous ovarian carcinoma (MOC) is a unique subtype of ovarian cancer with an uncertain etiology, including whether it genuinely ..

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When Is "Type I" Ovarian Cancer Not "Type I"? Indications of an Out-Dated Dichotomy

Carolina Salazar, Ian G Campbell, Kylie L Gorringe

2018-12-21

The dualistic classification of epithelial ovarian cancer (EOC) into "type I" and "type II" is widely applied in the research sett..

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Mutational landscape of mucinous ovarian carcinoma and its neoplastic precursors

Georgina L Ryland, Sally M Hunter, Maria A Doyle, Franco Caramia, Jason Li, Simone M Rowley, Michael Christie, Prue E Allan, Andrew N Stephens, David DL Bowtell, Ian G Campbell, Kylie L Gorringe

2015-08-07

BACKGROUND: Mucinous ovarian tumors are an unusual group of rare neoplasms with an apparently clear progression from benign to bor..