EXTEND-IA randomized trial of intra-arterial clot retrieval in ischemic stroke

Grant number: 1043242 | Funding period: 2013 - 2015

Completed

Abstract

Most strokes are caused by a blocked blood vessel in the brain. Current treatments to dissolve the blockage improve recovery for many patients but often fail to unblock larger brain arteries. The EXTEND-IA trial will use advanced brain imaging to identify patients who have the most to gain if the blocked artery can be re-opened. The trial will test whether a new minimally invasive clot removal procedure performed after standard clot-dissolving treatment improves recovery after stroke.

Related publications (7)

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Stroke is a major cause of death and disability globally. Diagnosis depends on clinical features and brain imaging to differentiat..

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Penumbral imaging and functional outcome in patients with anterior circulation ischaemic stroke treated with endovascular thrombectomy versus medical therapy: a meta-analysis of individual patient-level data

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Endovascular stent thrombectomy: the new standard of care for large vessel ischaemic stroke

Bruce CV Campbell, Geoffrey A Donnan, Kennedy R Lees, Werner Hacke, Pooja Khatri, Michael D Hill, Mayank Goyal, Peter J Mitchell, Jeffrey L Saver, Hans-Christoph Diener, Stephen M Davis

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State of Acute Endovascular Therapy Report From the 12th Thrombolysis, Thrombectomy, and Acute Stroke Therapy Conference

Pooja Khatri, Werner Hacke, Jens Fiehler, Jeffrey L Saver, Hans-Christoph Diener, Martin Bendszus, Serge Bracard, Joseph Broderick, Bruce Campbell, Alfonso Ciccone, Antoni Davalos, Stephen Davis, Andrew M Demchuk, Diederik Dippel, Geoffrey Donnan, David Fiorella, Mayank Goyal, Michael D Hill, Edward C Jauch, Tudor G Jovin

2015-06-01

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Endovascular Therapy for Ischemic Stroke with Perfusion-Imaging Selection

BCV Campbell, PJ Mitchell, TJ Kleinig, HM Dewey, L Churilov, N Yassi, B Yan, RJ Dowling, MW Parsons, TJ Oxley, TY Wu, M Brooks, MA Simpson, F Miteff, CR Levi, M Krause, TJ Harrington, KC Faulder, BS Steinfort, M Priglinger

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Imaging selection in ischemic stroke: feasibility of automated CT-perfusion analysis

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2015-01-01

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