Antibody-Dependent Cellular Cytotoxicity Based Immunity To Influenza
Grant number: 1042634 | Funding period: 2013 - 2015
Pandemic influenza causes widespread disease, death and panic. Producing vaccines to new strains takes time. There is a need to produce vaccines that provide partial protection against unknown strains. We identified a type of anti-influenza antibody in people with prior influenza infection that may assist in reducing disease from new influenza strains. We will study these antibodies, understanding how effective they against influenza, with a view to making improved anti-influenza vaccines.
Related publications (1)
Antibody Responses with Fc-Mediated Functions after Vaccination of HIV-Infected Subjects with Trivalent Influenza Vaccine
Anne B Kristensen, William N Lay, Fernanda Ana-Sosa-Batiz, Hillary A Vanderven, Vijaya Madhavi, Karen L Laurie, Louise Carolan, Bruce D Wines, Mark Hogarth, Adam K Wheatley, Stephen J Kent