Role of kinesin binding protein and spontaneous activity in the development of enteric neurons

Grant number: 1047953 | Funding period: 2013 - 2016

Completed

Abstract

The nerve cells in the wall of the gut play an essential role in motility. Defects in the development of these nerve cells results in pediatric motility disorders. We will examine the roles of two factors, kinesin binding protein, and spontaneous activity in the development of enteric neurons.

Related publications (13)

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Kif1bp loss in mice leads to defects in the peripheral and central nervous system and perinatal death

Caroline S Hirst, Lincon A Stamp, Annette J Bergner, Marlene M Hao, Mai X Tran, Jan M Morgan, Matthias Dutschmann, Andrew M Allen, George Paxinos, Teri M Furlong, Sonja J McKeown, Heather M Young

2017-11-30

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Spontaneous calcium waves in the developing enteric nervous system

Marlene M Hao, Annette J Bergner, Caroline S Hirst, Lincon A Stamp, Franca Casagranda, Joel C Bornstein, Werend Boesmans, Pieter Vanden Berghe, Heather M Young

2017-08-01

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Exposure to GDNF Enhances the Ability of Enteric Neural Progenitors to Generate an Enteric Nervous System

Sonja J McKeown, Mitra Mohsenipour, Annette J Bergner, Heather M Young, Lincon A Stamp

2017-02-14

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Development of the intrinsic and extrinsic innervation of the gut

Toshihiro Uesaka, Heather M Young, Vassilis Pachnis, Hideki Enomoto

2016-09-15

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Hirschsprung disease - laying down a suitable path

Heather M Young, Sonja J McKeown

2016-01-01

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Changes in Nicotinic Neurotransmission during Enteric Nervous System Development

Jaime Pei Pei Foong, Caroline S Hirst, Marlene M Hao, Sonja J McKeown, Werend Boesmans, Heather M Young, Joel C Bornstein, Pieter Vanden Berghe

2015-05-06

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Ion Channel Expression in the Developing Enteric Nervous System

Caroline S Hirst, Jaime PP Foong, Lincon A Stamp, Emily Fegan, Stephan Dent, Edward C Cooper, Alan E Lomax, Colin R Anderson, Joel C Bornstein, Heather M Young, Sonja J McKeown

2015-03-23

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Different Neural Crest Populations Exhibit Diverse Proliferative Behaviors

David G Gonsalvez, Mathew Li-Yuen-Fong, Kylie N Cane, Lincon A Stamp, Heather M Young, Colin R Anderson

2015-03-01

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All Is Not Normal in "Normoganglionic" Bowel Regions of Hirschsprung Disease Model Mice

Heather M Young

2015-01-01

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Colonizing while migrating: how do individual enteric neural crest cells behave?

Heather M Young, Annette J Bergner, Matthew J Simpson, Sonja J McKeown, Marlene M Hao, Colin R Anderson, Hideki Enomoto

2014-03-26

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Birthdating of Myenteric Neuron Subtypes in the Small Intestine of the Mouse

Annette J Bergner, Lincon A Stamp, David G Gonsalvez, Margaret B Allison, David P Olson, Martin G Myers, Colin R Anderson, Heather M Young

2014-02-15

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Development of myenteric cholinergic neurons in ChAT-Cre;R26R-YFP Mice

Marlene M Hao, Joel C Bornstein, Heather M Young

2013-10-01

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Genetic fate-mapping of tyrosine hydroxylase-expressing cells in the enteric nervous system

F Obermayr, LA Stamp, CR Anderson, HM Young

2013-04-01

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