Manipulation of enteric neural stem cells for cell therapy to treat enteric neuropathies

Grant number: 1043397 | Funding period: 2013 - 2016



Cell therapy offers great promise for the treatment of motility disorders due to defects in the nerve cells in the bowel. Patient-derived cells are likely to be the best source of cells, however, patient-derived cells will require manipulation because they are likely to be defective. We will identify manipulations of stem/progenitor cells that increase their efficacy for cell transplantation.