Investigating the interaction between BDNF and sex steroid hormones during adolescent development: relevance to schizophrenia

Effect of adolescent androgen manipulation on psychosis-like behaviour in adulthood in BDNF heterozygous and control mice

X Du, CR McCarthny, M Notaras, M van den Buuse, RA Hill

2019-06-01

RATIONALE: Males are more prone to psychosis, schizophrenia and substance abuse and addiction in adolescence and early adulthood t..

A role for the BDNF gene Val66Met polymorphism in schizophrenia? A comprehensive review

Michael Notaras, Rachel Hill, Maarten Van den Buuse

2015-04-01

Schizophrenia is believed to arise from complex gene-environment interactions. Brain-derived neurotrophic factor (BDNF) is involve..

Analyzing the influence of BDNF heterozygosity on spatial memory response to 17 beta-estradiol

YWC Wu, X Du, M van den Buuse, RA Hill

2015-01-20

The recent use of estrogen-based therapies as adjunctive treatments for the cognitive impairments of schizophrenia has produced pr..

Sex differences in the adolescent developmental trajectory of parvalbumin interneurons in the hippocampus: A role for estradiol

YeeWen Candace Wu, Xin Du, Maarten van den Buuse, Rachel A Hill

2014-07-01

OBJECTIVE: Gender differences in the neurodevelopmental disorder, schizophrenia, have been described for nearly all features of th..