Systems biology of asthma development in early childhood
Grant number: 1049539 | Funding period: 2013 - 2016
Recent studies have established that both human genetic susceptibility and viral infections during early childhood are important drivers of asthma development. It has also been noted that asthmatics’ airways are colonized with different bacteria to non-asthmatics. In this project we will examine how genetic susceptibility and interactions between bacteria and viruses in children's airways promote the development of allergy and asthma.
Related publications (1)
Elucidation of pathways driving asthma pathogenesis: development of a systems-level analytic strategy
Michael L Walker, Kathryn E Holt, Gary P Anderson, Shu Mei Teo, Peter D Sly, Patrick G Holt, Michael Inouye
Asthma is a genetically complex, chronic lung disease defined clinically as episodic airflow limitation and breathlessness that is..