Uncovering the Role of Collecting Lymphatic Vessels in Cancer.

Abstract

Lymphatic vessels are a critical part of the circulatory system, allowing the return of fluid and cells that escape the blood vessels, and playing an intimate role in the body's immune function. In cancer, the lymphatic vessels serve as conduits for the transport of tumour cells to lymph nodes and may contribute to distant metastasis. Our study is designed to understand the role played by major collecting lymphatic vessels in cancer and to identify molecules that control their activity.

Related publications (1)

The evolving role of lymphatics in cancer metastasis

Rae H Farnsworth, Marc G Achen, Steven A Stacker

2018-08-01

While the link between the lymphatic system and the metastatic spread of cancer is centuries old, understanding of the underlying ..