AGE-RELATED IMPAIRMENT OF AUTOREGULATION: A MODIFIABLE RISK FACTOR FOR GLAUCOMA
Grant number: 1046203 | Funding period: 2013 - 2016
The prevalence and incidence of glaucoma increase dramatically with age. An impaired capacity to buffer against physiological pressure fluctuations in the eye with aging may play a key role in the development of glaucoma. This project will use non-invasive imaging to determine if impaired autoregulation increases the risk of developing glaucoma. It will determine if this age-related decline in autoregulation can be restored and in this way provide protection against glaucoma.
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To consider whether a circumlimbal suture can be used to chronically elevate intraocular pressure (IOP) in mice and to assess its ..