LIPID ANTIGEN RECOGNITION BY DIVERSE CD1-RESTRICTED T CELLS

Grant number: 1054431 | Funding period: 2013 - 2017

Completed

Abstract

Natural Killer T (NKT) cells are a specialized T cell lineage that form a key part of the adaptive immune response required for protection against infection, allergy, cancer and autoimmune diseases. Different types of NKT cells exist, expressing distinct T cell receptors that recognize a large array of lipid antigens presented during disease conditions. Understanding the mechanisms involved in lipid recognition is crucial in deciphering how NKT cells can be manipulated for desired immune responses.

Related publications (5)

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