Wiring the gut's nervous system: formation and maturation of synapses
Grant number: DP130101596 | Funding period: 2013 - 2016
This project aims to determine how nerve circuits controlling intestinal functions develop; specifically how communication between specific nerve cells is established once they appear in the embryonic gut. It will fill a major hole in existing knowledge of mechanisms regulating the development of normal digestive behaviours.
Related publications (8)
alpha-Synuclein Regulates Development and Function of Cholinergic Enteric Neurons in the Mouse Colon
M Swaminathan, C Fung, D Finkelstein, JC Bornstein, JPP Foong
Alpha-Synuclein (α-Syn) is expressed in the central nervous system and the nervous system of the gut (enteric nervous system, ENS)..
Optogenetic Demonstration of Functional Innervation of Mouse Colon by Neurons Derived From Transplanted Neural Cells
Lincon A Stamp, Rachel M Gwynne, Jaime PP Foong, Alan E Lomax, Marlene M Hao, David I Kaplan, Christopher A Reid, Steven Petrou, Andrew M Allen, Joel C Bornstein, Heather M Young