MOLECULAR SUBTYPESOF HIGH GRADE SEROUS OVARIAN CANCER - LEVERAGING OF TCGA, OCAC, OTTA, AND AOCS GENOME AND GENOMIC DATASETS

Grant number: W81XWH-12-1-0104 | Funding period: 2012 - 2014

Completed

Abstract

PUBLIC ABSTRACT More and more, researchers are learning that ovarian cancer is not one disease but, rather, a number of distinct diseases with different genetic, and likely different environmental, risk factors. However, we still treat ovarian cancer as if it were a single disease, and, sadly, many women simply do not respond to current treatment options. Treatment improvements rely on understanding how tumors differ from each other and targeting treatment accordingly. This proposal explores a newly recognized and important aspect of tumor difference in women with high-grade serous cancer, the most common and deadly form of ovarian cancer. Ovarian tumors are diagnosed by pathologists based o..

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University of Melbourne Researchers