The genetic architecture and evolution of quantitative traits
Grant number: DP130100563 | Funding period: 2013 - 2016
Most important traits are controlled by many genes and by the environment, however there is little knowledge of how many genes are involved in these complex traits and what their effects are. This project will describe the number of genes and their effects for complex traits in humans and livestock and explain how these genes evolve.
Related publications (2)
Genetics of complex traits: prediction of phenotype, identification of causal polymorphisms and genetic architecture
ME Goddard, KE Kemper, IM MacLeod, AJ Chamberlain, BJ Hayes
Complex or quantitative traits are important in medicine, agriculture and evolution, yet, until recently, few of the polymorphisms..
Risk of psychiatric illness from advanced paternal age is not predominantly from de novo mutations
Jacob Gratten, Naomi R Wray, Wouter J Peyrot, John J McGrath, Peter M Visscher, Michael E Goddard
The offspring of older fathers have higher risk of psychiatric disorders such as schizophrenia and autism. Paternal-age-related de..