How does Redox Cycling Drive the Metabolism of the Essential Metals Iron and Copper?
Grant number: DP130100728 | Funding period: 2013 - 2016
Iron and copper are essential metal nutrients but mishandling leads to cardiovascular, metabolic and neurological disease. Intriguingly, some enzymes handle both iron and copper and this project will develop new methods for their study. The work will lead ultimately to enlightened prevention and effective management of the multiple diseases.
Related publications (4)
Copper ATPase CopA from Escherichia coli: Quantitative Correlation between ATPase Activity and Vectorial Copper Transport
Chathuri JK Wijekoon, Saumya R Udagedara, Roland L Knorr, Rumiana Dimova, Anthony G Wedd, Zhiguang Xiao
Cu-ATPases are membrane copper transporters present in all kingdoms of life. They play a central role in Cu homeostasis by pumping..