EXTENDING FRONTIERS OF STRUCTURAL CHEMISTRY AND BIOLOGY THROUGH HIGH RESOLUTION PULSED ELECTRON PARAMAGNETIC RESONANCE

A Functional Role for A in Metal Homeostasis? N-Truncation and High-Affinity Copper Binding

Mariusz Mital, Nina E Wezynfeld, Tomasz Fraczyk, Magdalena Z Wiloch, Urszula E Wawrzyniak, Arkadiusz Bonna, Carolin Tumpach, Kevin J Barnham, Cathryn L Haigh, Wojciech Bal, Simon C Drew

2015-09-01

Accumulation of the β-amyloid (Aβ) peptide in extracellular senile plaques rich in copper and zinc is a defining pathological feat..

The N Terminus of alpha-Synuclein Forms Cu-II-Bridged Oligomers

Simon C Drew

2015-05-04

The oligomerization of α-synuclein (αSyn) is one of the defining features of Parkinson's disease. Binding of divalent copper to th..