Extending Frontiers of Structural Chemistry and Biology Through High Resolution Pulsed Electron Paramagnetic Resonance

A Functional Role for Aβ in Metal Homeostasis? N-Truncation and High-Affinity Copper Binding

M Mital, NE Wezynfeld, T Frączyk, MZ Wiloch, UE Wawrzyniak, A Bonna, C Tumpach, KJ Barnham, CL Haigh, W Bal, SC Drew

2015-09-01

Accumulation of the β-amyloid (Aβ) peptide in extracellular senile plaques rich in copper and zinc is a defining pathological feat..

A Functional Role for Aβ in Metal Homeostasis? N‐Truncation and High‐Affinity Copper Binding

Mariusz Mital, Nina E Wezynfeld, Tomasz Frączyk, Magdalena Z Wiloch, Urszula E Wawrzyniak, Arkadiusz Bonna, Carolin Tumpach, Kevin J Barnham, Cathryn L Haigh, Wojciech Bal, Simon C Drew

2015-09-01

<jats:title>Abstract</jats:title><jats:p>Accumulation of the β‐amyloid (Aβ) peptide in extracellular senile plaques rich in copper..