NOVEL TARGETED PET NANOPARTICLES FOR DIAGNOSIS OF THROMBOSIS, INFLAMMATION AND PREVENTION OF MYOCARDIAL INFECTION.
Grant number: 1029249 | Funding period: 2012 - 2014
The aim of this project is to develop novel targeted positron emission tomography imaging agents that seek out specific markers for various states of cardiovascular disease. These agents would provide a method for detecting the presence and level of atherosclerosis and thrombotic events. The targeted nanoparticles may provide a unique opportunity to detect very early plaques and the vulnerability of existing plaques.
Related publications (1)
Boronate-Phenolic Network Capsules with Dual Response to Acidic pH and cis-Diols
Junling Guo, Huanli Sun, Karen Alt, Blaise L Tardy, Joseph J Richardson, Tomoya Suma, Hirotaka Ejima, Jiwei Cui, Christoph E Hagemeyer, Frank Caruso
Dual-responsive boronate-phenolic network (BPN) capsules are fabricated by the complexation of phenylborate and phenolic materials..