Systems Biology Of Asthma Development In Early Childhood

Abstract

Recent studies have established that both human genetic susceptibility and viral infections during early childhood are important drivers of asthma development. It has also been noted that asthmatics’ airways are colonized with different bacteria to non-asthmatics. In this project we will examine how genetic susceptibility and interactions between bacteria and viruses in children's airways promote the development of allergy and asthma.

Related publications (1)

Elucidation of pathways driving asthma pathogenesis: development of a systems-level analytic strategy

Michael L Walker, Kathryn E Holt, Gary P Anderson, Shu Mei Teo, Peter D Sly, Patrick G Holt, Michael Inouye

2014-09-23