[[[UNIVERSITY OF MELBOURNE AI ONLY]]] RENAL DENERVATION TO IMPROVE OUTCOMES IN PATIENTS WITH END-STAGE RENAL DISEASE

Abstract

End stage renal disease is associated with excess cardiovascular morbidity and mortality. Activation of sympathetic nerves plays an important role in this scenario. We have pioneered a novel catheter-based approach using radiofrequency-energy to disrupt these nerves and we now aim to assess the mechanisms and consequences of applying this novel technology in patients with end-stage renal disease.